A STUDY OF CREATINE PHOSPHOKINASE LEVELS IN CEREBROSPINAL FLUID AND SERUM IN PATIENTS OF PYOGENIC AND TUBERCULAR MENINGITIS
Journal Title: International Journal of Basic and Applied Physiology - Year 2018, Vol 7, Issue 1
Abstract
Creatine phosphokinase was measured serially in cerebrospinal fluid (CSF) and serum in forty patients, twenty each of pyogenic and tubercular meningitis. Twenty healthy cases act as control. The aim of the study is to find whether creatine phosphokinase levels has any diagnostic or prognostic significance in serum and C.S.F in cases of pyogenic and tubercular meningitis. Material and method: The enzymatic activity was measured serially on (1st, 3rd and 5th day) in cases of pyogenic meningitis and (1st, 3rd, 7th and 14th day) in tubercular meningitis. The clinical details including the level of consciousness, neurological deficit and mortality were correlated with the enzymatic activity and prognosis. Results: In pyogenic meningitis creatine phosphokinase activity in C.S.F. was raised on 1st day as comparison to tubercular meningitis it was on 3rd day of admission and progressively dropped to significantly lower values with the recovery of the patient. Definite correlation was demonstrated between the enzyme activity in C.S.F. and level of consciousness, mortality in cases of tubercular and pyogenic meningitis. Conclusion: Creatine phosphokinase activity in cerebrospinal fluid has a diagnostic and prognostic value in patients of pyogenic and tubercular meningitis.
Authors and Affiliations
Ankur wadhwa, Rampure Dilip, Irshad Hussain Askari
Keywords
Related Articles
- EP ID EP538514
- DOI -
- Views 67
- Downloads 0
EVALUATION OF HEARING ACUITY IN YOUNG ADULTS USING PERSONAL LISTENING DEVICES WITH EARPHONES
Background: There is a growing concern regarding the hearing health of the young adults, because now a day the usage of personal listening devices and mobile phones with earphone or headphones has increased tremendously...
ASSOCIATION OF VIABILITY OF MYOCARDIUM WITH PARAMETERS OF HEART RATE VARIABILITY IN PATIENTS OF FIRST ANTERIOR MYOCARDIAL INFARCTION
Background & Objective: Heart rate variability (HRV) is depressed after acute myocardial infarction (MI) and has been considered as a powerful predictor of mortality and arrhythmic complications in patients of MI. The pr...
NUCLEO-CYTOPLASMIC ALTERATIONS OF BUCCAL CELLS IN IRON DEFICIENCY ANEMIA.
Background & Objectives: Although iron deficiency is associated with constant involvement of oral mucosa, the effect of iron on cell cycle inhibitory molecules has been superficially studied. The present study was undert...
INTRODUCTION OF INTEGRATED TEACHING IN I st MBBS: PERSPECTIVE OF STUDENTS
AIMS AND OBJECTIVES: study was carried out to focus on effective and meaningful learning that will help the students’ overall development and to improve the continuity of students’ learning. MATERIAL AND METHOD: 150 stud...
A COMPARATIVE STUDY OF SERUM TRIGLYCERIDE BETWEEN PRE-ECLAMPTIC PRIMIGRAVIDA & NORMAL PRIMIGRAVIDA.
Background: Various physiological & biochemical alterations occur during human pregnancy.Pre-eclampsia is common medical complication with high morbidity & mortality to both mother as well as fetus. Aim:To corelate chang...