A study of interaction of cigarette smoke with alpha-1 antitrypsin and adenosine deaminase in patients of chronic obstructive pulmonary diseases (COPD) and antioxidant role of vitamin E
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2018, Vol 5, Issue 4
Abstract
Lungs are the only organs which are continuously exposed to external environment through the process of breathing The cigarette smoking is main leading cause of various morbidities related to lungs Adenosine deaminase ADA and alpha1 antitrypsin A1AT are the two very important parameters of which ADA is required for maintaining proper immunity and A1AT is required for resolving oxidant stress on lungs by various mechanism In the present study we evaluated the level of these parameters in active cigarette smokers without lung disease and COPD patients and found that ADA level was significantly high in healthy smokers and COPD patients as compared to healthy controls PKeywords Adenosine deaminase Alpha1 antitrypsin Chronic obstructive pulmonary diseases COPD Vitamin E and Cigarette smoke CS
Authors and Affiliations
Dhananjay V Andure, Anita M. Raut, Ramchandra K. Padalka, Sangita M. Patil, Sonali S. Bhagat
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