A STUDY OF SEROPREVALENCE AND CHANGING TREND OF DENGUE IN A TERTIARY CARE HOSPITAL IN MANIPUR
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 31
Abstract
BACKGROUND Dengue fever is a seasonal and emerging acute mosquito borne arbo-viral illness affecting tropical and sub-tropical countries. This illness ranges from mild asymptomatic form to severe dengue haemorrhagic fever with or without dengue shock syndrome. In India, the epidemiology of dengue virus infection is very complex and ever changing. Infection has expanded over the last two decades to all regions of the country including hilly states of the north-eastern region (Assam, Arunachal Pradesh, Nagaland and Manipur). Aim- To identify dengue seropositive patients by NS1 antigen and anti-dengue IgM antibody detection by ELISA and correlate the changes in epidemiology. MATERIALS AND METHODS A cross-sectional study done from January 2016 to December 2017 with blood samples tested from clinically suspected cases of dengue virus infection. RESULTS During the study period from January 2016 to December 2017, a total of 1569 blood samples were tested, of which 251 were in 2016 and 1318 cases were in 2017. In the year 2016, 35 (13.94%) were NS1 positive, 18 (7.17%) were IgM positive and total dengue positive in 2016 was 53 (21.11%). In 2017, 208 (15.70%) were IgM positive and there were no NS1 positive cases in this year. Maximum number of positive cases, 85 (41.46%) belonged to age group 15-30 years in 2017 and 18 (33.96%) in the age group of 15-30 years in 2016 also. CONCLUSION Prevalence of dengue seropositive cases was 53 (21.11%) in 2016 and 208 (15.70%) in 2017 indicating a rapid decline in dengue infection, which may be attributable to the collective efforts taken by the healthcare workers and by the people during the timely delivery of preventive and control measures besides having increased awareness among the people.
Authors and Affiliations
L. Kokindro Singh, Chitra Yengkokpam, L. Shivadutta Singh, H. Lokhendro Singh
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