Accuracy of Fnac in Diagnosing Thyroid Nodules: A Single Institution Experience
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2017, Vol 1, Issue 4
Abstract
Background: FNA is the first-line investigation in the diagnosis of thyroid nodules. Aims: To determine the accuracy of FNAC in diagnosing thyroid nodules. To identify the major cause of discrepancy in FNAC reports Methods: The final histopathology report (HPR) of all thyroidectomies done from January 2008 to December 2010 was retrieved by a retrospective search in institutional databases. Corresponding FNAC reports were also retrieved. The correlation between FNAC and final histopathology was studied to determine the accuracy with which FNAC diagnosed thyroid disorders. Results: The sensitivity and specificity of FNAC in diagnosing benign nodules is 92% and 71.6% respectively. A. The sensitivity and specificity of FNAC for diagnosis of neoplasm is 81.6% and 92% respectively. B. The sensitivity and specificity of FNAC for diagnosis of malignancy is 87.8% and 98.2% respectively. Conclusion: FNA is highly sensitive and specific in the diagnosis of thyroid nodules. Cytological similarities between hyperplasic nodule and follicular neoplasm are a major source of error.
Authors and Affiliations
Ajay Kumar B, Sreejayan MP, Vaisagh Remin
Keywords
Related Articles
- EP ID EP570037
- DOI 10.26717/BJSTR.2017.01.000352
- Views 177
- Downloads 0
Time-Dependent Bactericidal Efficacy of Hydrogen Peroxide against Methicillin-Resistant Staphylococcus Aureus and Acinetobacter Baumannii in Second Degree Burn Wound
Nosocomial infections are major health care problem and their developing antibiotics resistance have made it harder to treat. Hydrogen peroxide (H2O2) is widely used for contaminated wound sterilization, but its efficacy...
Pain Related to External Injury and Disorders Associated with Psychosocial Factors
In many sports, there are cases in which psychosocial factors are involved in the onset and persistence of lower back and lower limb pain. For example, the diagnostic guidelines for chronic pain and lumbar disc herniatio...
Rare Presentations of Metastatic Renal Cell Carcinoma with Hematochezia and Anemia
Renal cell carcinoma (RCC) is the sixth most common cancer in men and the eighth most common cancer in women in the United States, with an estimated 65,150 new cases diagnosed in 2013 [1]. RCC’s classic presenting triad...
Evaluation of Physical Activity in a Group of Physically Inactive Individuals from a Government Corporation
Modern societies are undergoing considerable changes, such as the increase of physical inactivity. Epidemiological and scientific studies report that physical activity is related to reduced morbidity and mortality fr...
Metabolic and Biochemical Profiling of Phenolic Compound and their Biosynthesis in Oil Crops
The oil seed crops are the important sources of phenolic compounds in the human diet. Important oil seed crops include olive and soybean. In Virgin olive oil (VOO) Phenolic compounds is present which are important in reg...