Accuracy of Imaging Methods for Diagnosing Acute Cholecystitis
Journal Title: Гастроентерологія - Year 2015, Vol 1, Issue 55
Abstract
The study was conducted to evaluate the diagnostic accuracy for acute cholecystitis, acute cholangitis and to get summary data. Information search of results of clinical trials, systematic reviews, meta-analysis, clinical guidelines regarding the sensitivity and specificity of hepatobiliary scintigraphy, US, MR, , CT scanning in acute cholangitis was conducted in Cochranelibrary, Medline/PubMed and other search systems by key words: gallstone disease, acute cholecystitis, ultrasonography , cholescintigraphy, computer tomography, magnetic resonance tomography, sensitivity, specificity from January 2000 to February 2014. Inclusion criteria: a) clear criteria for determining a positive result visualization, b) operation and/or clinical observations were used as a reference, and c) there are enough data to estimate the number of true positive, negative results, false-positive and false-negative results. In a study evaluating hepatobiliary scintigraphy sensitivity of 88.5 % (95% CI: 81–97 %) and specificity of 91.8 % (95% CI: 86–93 %) were comparable with the data of 2012, but slightly lower sensitivity was revealed in our study. Sensitivity was 84.4 % (95% CI: 76–93 %) with specificity of 85.1 % (95% CI: 78–91 %) for studies evaluatining ultrasonography, which is slightly higher than those obtained in a systematic survey in 2012. We have shown that magnetic resonance imaging and ultrasonography did not reveal statistically significant differences in the diagnosis of gallbladder wall thickening, presence of gallstones, pericholesistic liquid or acute cholecystitis (p > 0.05). Sensitivity of acute cholecystitis comprised 89.4 % (95% CI: 85–91 %) and specificity was 87.2 % (95% CI: 83–99 %) for magnetic resonance imaging. This method is equal to ultrasonography in the diagnosis of cholelithiasis disease, gallbladder wall thickening, determining the presence of pericholesistic edema and acute cholecystitis in patients with acute pain symptoms in the right upper abdominal quadrant. Especially in patients with sonographic complexity magnetic resonance imaging can be used as a quick and easy method of diagnosis.
Authors and Affiliations
I. Yu. Skyrda, V. М. Gladun, О. V. Zakrevska
Keywords
Related Articles
- EP ID EP214722
- DOI -
- Views 76
- Downloads 0
Short-chain fatty acids: the role in the development of irritable bowel syndrome
The article deals with the concepts of irritable bowel syndrome. A brief analysis of probable factors of irritable bowel syndrome development was performed. The role of intestinal microflora and the contribution of short...
The Evolution of the Treatment of Acid-Related Diseases
The article describes the main stages of the development and improvement of antisecretory therapy, from antacids to modern proton pump inhibitors (PPIs). It is concluded that at present the main drugs for the treatment o...
Significance of intestinal metaplasia and dysplasia in morphological diagnosis of patients with chronic reflux gastritis
The present study was undertaken to analyze biopsies in 120 cases of chronic reflux gastritis with the help of modern histological, histochemical and morphometric methods. Histological study showed atrophic processes in...
The Epidemiologic Peculiarities of Inflammatory Bowel Diseases According To Data from State Institution «Institute of Gastroenterology of National Academy of Medical Sciences of Ukraine»
A retrospective analysis of case histories of 843 patients with ulcerative colitis and 222 — with Crohn’s disease who were treated at the State Institution «Institute of Gastroenterology of National Academy of Medical Sc...
The Role of Elastase Antibodies, Circulating Autoantibodies to Glutamate Decarboxylase and Islet Cells Antigens in Chronic Pancreatitis
The article presents an analysis of the occurrence of elastase antibodies, circulating autoantibodies to glutamate decarboxylase and islet cells antigens in different forms of chronic pancreatitis. In all patients with c...