AN EFFICIENT TREATMENT OF YEAST INFECTION OF WHITE PATCHES IN SKIN BY NATURAL REMEDY
Journal Title: International Journal of Pharmaceutical Applications - Year 2011, Vol 2, Issue 4
Abstract
White patches are a de pigmenting disorder of the skin. Occasionally, the loss of melanin (ie, hypopigmentation) is partial. The major cause for this disease is found to be yeast Candida species. Commercially available natural raw materials such as lemon peel and hypo (Sodium hyposulfite) are used for this study. The extracts are separated by continuous hot extraction process using soxhlet apparatus with different solvents like chloroform, ethyl acetate, ethanol, acetone and aqueous in the order of their polarity. The qualitative and quantitative analysis of the phytoconstituents like alkaloids, glycosides, flavonoids, saponin, tannins, phenolic compounds, ascorbic acid contents, was studied. The antimicrobial and antifungal activity of different extracts was tested against different bacteria and fungi using agar well diffusion method with ampicillin and nystatin as positive standard reference to determine the sensitivity of the bacterial and fungal strains. Antioxidant activity of these extract with different concentration were calculated using DPPH assay. Highest scavenging effect of the extract was also studied by comparison of various extracts obtained. The result revealed that sodium hyposulphite and lemon juice showed the better antifungal activity and antioxidant activity. Combinations of lemon and sodiumhypo sulphite were used for alternate treatment of yeast infection on skin. An ointment was formulated using paraffin wax as emulsifier at concentration of 50% against the combined extract.
Authors and Affiliations
Ayyappadasan . G , Khushbu singh . R , Ponmurugan. P
Keywords
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