AN OBSERVATIONAL STUDY ON ADVERSE CUTANEOUS DRUG REACTION IN A TERTIARY CARE CENTRE
Journal Title: PARIPEX-Indian Journal of Research - Year 2017, Vol 6, Issue 11
Abstract
Aim : Drug reactions are unwanted reactions of the body following the administration of drugs and range from transient maculopapular rash to fatal toxic epidermal necrolysis (TEN). This study was undertaken to ascertain the clinical spectrum of adverse cutaneous drug reaction (ACDR) and the causative drugs, in a tertiary care centre. Materials and methods : An observational study conducted in Department of Dermatology at a tertiary care centre during the period of January -December 2016. Severity of the reaction assessed using World Health Organisation-Uppsala Monitoring Centre (WHO-UMC) criteria. Results and conclusion: Fixed drug eruption (FDE) was the commonest ACDR. Females outnumbered males. More cases reported in elderly patients in the age group of 18-40 years. Antibiotics were the common drug to cause ACDRs followed by antiepileptics. Knowledge of these drug eruptions are essential for the treating clinician.
Authors and Affiliations
Suganthy R Rajakumari, Thirumalai Nambi. T
Keywords
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