An overview on the national burden of tuberculosis and its current status
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2015, Vol 4, Issue 4
Abstract
Tuberculosis (TB) still remain a major challenging global health problem. India is one the high TB burden country, adding to 26 per cent of the worldwide TB burden. During the 20th century, TB became treatable and the therapeutic success of short-course chemotherapy was a break through. In the early 1980s, human immunodeficiency virus (HIV) infection/acquired immunodeficiency syndrome (AIDS) pandemic resulted in a resurgence of TB globally with more complications and challenges like occurrence of multidrug-resistant and extensively drug-resistant TB (M/XDR-TB). Atypical clinical presentation still poses a challenge. While treatment of TB and HIV-TB co-infection has become simpler, efforts are on to shorten the treatment duration. However, drug toxicities, adverse drug reactions and drug-drug interactions still possess a significant challenge. Hurdles like the lack of adequate coverage, low economy and weak health services limit access to high-quality tuberculosis care in some of the countries. Further, many public and private health-care providers remain delinked from national tuberculosis control efforts. In addition, tuberculosis is a disease of the poor and the absence of universal health coverage aggravates the economic burden of TB on the poor. Even though the advancements in tuberculosis control over the past two decades are strong, relatively high effort is needed to wipe out the pandemic. A pursuit for novel biomarkers for predicting a durable cure, relapse, discovery/repurposing of newer anti-TB drugs, development of newer vaccines continues to attain the goal of eliminating TB altogether by 2050. The present review focuses on the global and Indian tuberculosis situation. It emphasizes the epidemiological situation in India and the burden of disease in the nation over time.
Authors and Affiliations
Keerthy J
Keywords
Related Articles
- EP ID EP411010
- DOI -
- Views 120
- Downloads 0
A cross sectional study of hair dye use among doctors and nurses working at a tertiary care centre
Background Hair dye products are being extensively used worldwide to enhance an individual outlook. More than two thirds of hair dyes currently contain PPD (paraphenelenediamine) which is a potent allergen and also a ca...
Terminalia catappa: A potential herb to promote hair growth, preliminary preclinical study
Hair loss problem is of great significance to both men and women. The essential issues associated with hair loss are hair fading, dandruff, and falling of hair. Alopecia is the medical term for hair loss or baldness. It...
Evaluation of hypoglycaemic activity of shilajit in alloxan induced diabetic rats
Background Diabetes mellitus is a potentially morbid condition with high prevalence worldwide. This disease constitutes a major health concern affecting about 2.8% of the global population. Currently available synthetic...
An observational study on safety profile of ofloxacin and levofloxacin in treatment of acute exacerbation of chronic bronchitis
Background COPD is predicted to be the third most common cause of death and chronic disability in the world by 2020. The term COPD encompasses several conditions. These include airflow obstruction with little reversibil...
A case report on management of sero negative spondyloarthropathy
Spondyloarthropathies are a family of long-term (chronic) diseases of joints. These diseases occur in children (juvenile spondyloarthropathies) and adults. They include ankylosing spondylitis, reactive arthritis, psoriat...