Terminalia catappa: A potential herb to promote hair growth, preliminary preclinical study
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2019, Vol 8, Issue 1
Abstract
Hair loss problem is of great significance to both men and women. The essential issues associated with hair loss are hair fading, dandruff, and falling of hair. Alopecia is the medical term for hair loss or baldness. It is an embarrassing condition for any person as he/she looks extra aged than ordinary. Many forms of medication are available to treat alopecia in special procedure of medication such as Allopathic, Homeopathic, and Ayurveda or can also be surgical like hair transplantation; however, none of them is wholly ample. This hindrance could be solved by the use of natural medicines obtained from herbs. Terminalia catappa Linn belongs to the family Combretaceae and is popularly known as ‘deshi badam’. It is a well known herb in Ayurvedic system of medicine. Almost all the parts of Terminalia catappa were significantly employed in various ailments. The seed extract of Terminalia catappa was claimed to have hair growth promotion property. Current study was conducted with an aim to evaluate the hair growth promotion activity of ethanolic seed extract of Terminalia catappa. The extract was mixed in coconut oil, applied on the shaved area of rats and qualitative hair growth analysis was undertaken by observing hair growth initiation time (Minimum time taken to initiate hair growth on denuded skin region), hair growth completion time (Minimum time taken to completely cover the denuded skin region with new hair) and mean hair length were measured. 2% Minoxidil was used as reference control and all the test drugs were applied once daily for 30 days. Ethanolic seed extract of Terminalia catappa significantly decreased the time taken for initiation of hair growth and hair growth completion time. Terminalia catappa significantly increased mean hair length size compared to vehicle treated. From the result it was concluded that Terminalia catappa promotes the hair growth in animal model.
Authors and Affiliations
Harsha Vardhan K
Keywords
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