Anti Cytotoxic And Microbial Studies Of Iron Schiff Base Complex With Azide
Journal Title: International Journal of Engineering and Science Invention - Year 2018, Vol 7, Issue 10
Abstract
The aim of this research is to study the role of Iron and the recognition of its complexes as important bioactive compounds in vitro and in vivo arouse an ever-increasing interest in these agents as potential drugs for therapeutic intervention in various diseases. Schiff bases are a critical class of compounds in medical chemistry that have verified significant chemotherapeutic and antibacterial application. Schiff base copper complexes revealed great potential for anti proliferative, anti bacterial, and gastro protective activity. orthophenylenediamine is a wide class of synthetic compound that showed diverse pharmacological activities including anticancer activity. In particular, their antibacterial, antifungal and anticancer activities make the compounds attractive for further derivatization and screening as novel therapeutic agents. Taking these compounds as iron, we have designed and synthesized a new iron complexe with ortho phenyline diamine, salicylaldehyde and Acetyl acetone Schiff base ligand.
Authors and Affiliations
M. S. N. A Prasad, E. Rajesh, A. Vasu Babu, B. Kishore Babu
Keywords
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