ANTIBACTERIAL ACTIVITY OF BIOLOGICALLY SYNTHESIS SILVER NANOPARTICLES FROM LEAF EXTRACT OF ALANGIUM SALVIFOLIUM (L.F) WANG
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2014, Vol 6, Issue 8
Abstract
Biologically Synthesis process of silver nanoparticles using plant extract is simple, cost-effective, and ecofriendly. In the present study, silver nanoparticles (AgNPs) were rapidly synthesized using Alangium salvifolium leaf extract. The nanoparticles obtained have been characterized with various techniques like UV-Visible spectrum, Scanning Electron Microscopy (SEM), Energy Dispersive Spectroscopy (EDAX), X-ray Diffraction (XRD) and Atomic Force Microscopy (AFM) and also tested antibacterial. These techniques showed the formations of AgNPs with an average size of 24.2 to 52.5 nm and also find the spherical shaped nanoparticles. The synthesized AgNPs had the potential to mitigate the bacterial proliferation against Staphylococcus aureus, Pseudomonas auroginosa, Bacillus thuringiensis, Escherichia coli, Klebsiella pneumonia and Salmonella typhi. The results were compared with the Ciprofloxacin as positive controls. It is concluded that the Alangium salvifolium is one of the best sources for synthesis of AgNPs and also showed good anti bacterial activity.Â
Authors and Affiliations
Mattegunta Linga Rao, Nataru Savithramma
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