ANTIBIOTIC UTILIZATION IN ACUTE EXACERBATION OF ASTHMA AND COPD
Journal Title: Int J of Pharm Rev& Res - Year 2015, Vol 5, Issue 1
Abstract
One of the most common reasons why patients are presented to the emergency departments or primary care physicians is due to exacerbation of their asthma or COPD symptoms. Excessive use of antibiotics has been a growing concern as it increases the antimicrobial resistance. Despite several guidelines on the management of exacerbations of asthma and COPD, the value of antibiotic in it remains extremely controversial. In this before-after retrospective study, 104 asthma and chronic obstructive pulmonary disease patients attending the out-patient department of Pulmonary Medicine of a medical college hospital in Hyderabad, India were recruited for the study. At two different visits patient’s prescriptions were assessed and data was collected. Comparisons were made between the two visits for the antibiotics prescribed. The results revealed that azithromycin was the most prescribed drug in both first (25%) and second (4.8%) visits, no antibiotic were prescribed to 42 subjects in the first visit whereas this number increases to 94 in the second visit. Amoxicillin+calvulonic acid, Cefepime+tazobactam, Cefpodoxime, cefuroxime, fluconazole and roxithromycin were prescribed in the first visit but not in the subsequent visit. The findings of this study reveal that, antibiotic prescription in exacerbations of asthma and COPD was due to underlying infection. The respiratory condition of the subjects was improved upon prescribed with an antibiotic for 3-5 days. The highest used antibiotic class was macrolide.
Authors and Affiliations
Mohammed Maazuddin1 , Mohd. Javeedullah1 , Mohd. Nasir Mohiuddin1
Keywords
Related Articles
- EP ID EP95689
- DOI -
- Views 162
- Downloads 0
FLOATING DRUG DELIVERY SYSTEM: A COMPREHENSIVE REVIEW AND ITS POSSIBLE SCOPE
In our day to day life oral dosage forms are known to be superior because of its advantages. Furthermore new Oral sustained release dosage forms (SRDFs) have been developed; however, this approach has not been suitable f...
PHYTOCHEMICAL AND PHARMACOGNOSTICAL EVALUATION OF PALASH PANCHANG (BUTEA MONOSPERMA LAM. KUNTZ.)
The present work deals with the pharmacognostical and prelimnary phytochemical study of Palash (Butea monosperma Lam. Kuntz.) panchanga (Rootbark, stembark, leaf, flower and seed). The purpose of this study is to determi...
CARDIOPROTECTIVE EFFECTS OF SAPONIN Momordica cymbalaria IN ISCHEMIA REPERFUSION INJURY
Momordica Cymbalaria has attracted steady attention in the last few years as phytomedicine possessing a wide spectrum of biological activities. In this study, saponins isolated from Momordica cymbalaria (SMC) was evaluat...
HEALTHCARE COMMUNICATIONS: ATTITUDES AND PERCEPTION OF PEOPLE ON THE USE OF SOCIAL MEDIA
Social media is one of the easiest ways of communication between business-to-business and business-to-consumer persons. There is a great lack of communications between people when it comes to healthcare and benefits asso...
IN VITRO ANTIOXIDANT ACTIVITY OF VARIOUS EXTRACTS/FRACTIONS OF IXORA PAVETTA
Free radicals play an important role in the development of tissue damage and pathological events in living organism. There is a compelling evidence indicates that increased consumption of antioxidants from fruits and veg...