ANTIOXIDANT/ANTIDEGRADATIVE EFFECTS OF TRICHOPUS ZEYLANICUS GAERTN AND GOMPHRENA CELOSIOIDES ON DEN/HCB INDUCED MALE ALBINO RATS
Journal Title: Journal of Medical Science And clinical Research - Year 2013, Vol 1, Issue 5
Abstract
Gomphrena celosioides crude and ethanol extract treatment. Thus the leaf T. zeylanicus and Gomphrena celosioides were found to have antioxidant /antidegradative activity. Trichopus zeylanicus is a plant with adaptogenic properties. This experiment with fourteen groups of rats was designed to evaluate the beneficial properties of T. zeylanicus and Gomphrena celosioides consumption on liver marker enzyme regulation and lipidperoxidation in albino rats in DEN/HCB induced stage. For the study, the male albino rats were divided into seven groups normal, chemical treated and chemical along with the crude and ethanol extract of plants treated groups for each phases,initiation and promotion. The Intraperitonial injection of DEN with one day and 83 days treatment of HCB caused carcinogenesis and the other group had plant treatment up to 90 days. Effects of T. zeylanicus and Gomphrena celosioides consumption on LPO and liver marker enzymes were also evaluated. The plant treatment had remarkable effects on LPO and liver marker enzymes level in the male albino rats. An improvement in lipidperoxidation and liver marker enzymes were observed with lower lipidperoxidation and liver marker enzymes after 90 days of T. zeylanicus and Gomphrena celosioides
Authors and Affiliations
A. MEENA
Keywords
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