Assessment of proximal extent of spread in squamous cell carcinoma esophagus
Journal Title: Medpulse International Journal of Surgery - Year 2018, Vol 6, Issue 3
Abstract
Background: Carcinoma of the esophagus is a devastating disease with adverse effects on swallowing and quality of life. The two most important prognostic factors for esophageal cancer are the depth of penetration and the nodal involvement. Aim: To assess the proximal extent of spread in squamous cell carcinoma esophagus. Material and Methods: Surgical specimens from 45 patients with Esophageal Squamous Cell Carcinoma who underwent Transhiatalesophagectomy were collected prospectively for study. The in situ length of esophagus from the proximal margin of the tumor to the proposed line of division measured first. Similarly, the length of resected specimen measured after stretching it in a corkboard to assess the percentage of shrinkage. Results: Among the 45 patients, in 4 patients the proximal extent of spread was <5mm, 28 patients it was 5 to 10 mm and in 13 atients it was >10mm. The maximum extent of proximal spread in our study was 15 mm. Mean proximal spread in our study group was 8.5 mm. When we compared the T-stage and the proximal spread, among the 28 T2 tumours,<5 mm proximal spread found in 4 patients and > 5 mm proximal spread in 24 patients. Among the 17 T3 lesions, all were found to have > 5 mm proximal spread. 10 of the T2 lesions found to have > 10 mm proximal spread, similarly 4 of the T3 lesions found to have > 10 mm proximal spread. Conclusion: To achieve consistently negative proximal resection margins we recommend resection of a minimum of 2 cm of macroscopically normal foregut above the proximal margin of the primary tumor
Authors and Affiliations
A Prabhakaran, Chandramohan 2, Naganath babu, Selvaraj 4, Amuthan 5, Ilango 6
Keywords
Related Articles
- EP ID EP361640
- DOI -
- Views 147
- Downloads 0
A study of factors associated with mortality in severe head injuryat tertiary health care centre
Background: Traumatic brain injury is leading cause of death and disability worldwide. Every year about 1.5 million affected people die and several millions receive emergency treatment. Aims and Objectives Aims and Objec...
Surgical outcomes of fascio-cutaneous rhomboid transposition flap surgery for pilonidal sinus- A case series
Aims: To analyze the possibility of complications, recurrence on follow-up and time taken to resume routine activity in cases of sacrococcygeal pilonidal sinus treated with fascio-cutaneous rhombic transposition flap rep...
A clinicopathological study and management of benign breast diseases in females
Background: Development and growth of breast are under the control of numerous hormones and various physiological states such as pregnancy and lactation. Benign breast disease is any nonmalignant breast condition and enc...
Assessment of proximal extent of spread in squamous cell carcinoma esophagus
Background: Carcinoma of the esophagus is a devastating disease with adverse effects on swallowing and quality of life. The two most important prognostic factors for esophageal cancer are the depth of penetration and the...
A study of the role of acute phase reactants – C-reactive protein and procalcitonin in predicting the severity of sepsis
Background: Sepsis is a serious clinical condition that represents a patient’s response to a severe infection and has a very high mortality rate. Aims and Objectives: to study the role of Acute phase reactants – C-reacti...