Biochemical Profile of Breast Cancer Patients Attended the Out-Patient Department of Cancer Unit, Mandalay General Hospital, Myanmar
Journal Title: JOURNAL OF BIOLOGICAL ENGINEERING RESEARCH AND REVIEW - Year 2017, Vol 4, Issue 2
Abstract
This experimental study was conducted to assess the biochemical profile including glucose, hepatic enzymes, renal biomarkers, uric acid and zinc levels of 36 newly-diagnosed cases of female breast cancer patients from the Out-Patient Department of Cancer Unit in Mandalay General Hospital, Myanmar. The parameters of breast cancer patients before the first cycle of chemotherapy were compared with those after the third cycle of chemotherapy; and also compared with those of apparently healthy controls. The baseline GPT and creatinine levels of patients were significantly higher, whereas urea and uric acid levels of patients were significantly lower than those of control subjects. Baseline uric acid and zinc levels of patients were significantly higher than those determined after the third cycle of chemotherapy. Therefore, these biochemical parameters may be useful in the treatment of breast cancer patients. Moreover, the patients should be carefully monitored during the course of treatment if they are treated with chemotherapeutic drugs that affect their biochemical profiles.
Authors and Affiliations
Kyae Mhon Htwe, Thet Oo Wai, Saw Ohmnmar Khin, Thandar Myint Thaw, Tin Moe Win, Yi Yi Myint
Keywords
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