BIOPHARMACEUTICS CLASSIFICATION SYSTEM: A STRATEGIC TOOL FOR CLASSIFYING DRUG SUBSTANCES
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 7
Abstract
The biopharmaceutical classification system (BCS) is a scientific approach for classifying drug substances based on their dose/solubility ratio and intestinal permeability. The BCS has been developed to allow prediction of in vivo pharmacokinetic performance of drug products from measurements of permeability and solubility. Moreover, the drugs can be categorized into four classes of BCS on the basis of permeability and solubility namely; high permeability high solubility, high permeability low solubility, low permeability high solubility and low permeability low solubility. The present review summarizes the principles, objectives, benefits, classification and applications of BCS.
Authors and Affiliations
Seema Rohilla , Ankur Rohilla , RK Marwaha , Arun Nanda
Keywords
Related Articles
- EP ID EP145488
- DOI -
- Views 83
- Downloads 0
EVALUATION OF “YAK001” FOR SAFETY PROFILE: ACUTE ORAL TOXICITY STUDY
This study determines acute toxicity of a coded drug “YAK001” an oral formulation prepared with suspension of test drug using gum acacia in rats. It was assessed for single dose acute toxicity by employing OECD guideline...
ULTRADEFORMABLE LIPID VESICLE AS A NOVEL DRUG DELIVERY SYSTEM
Various new technologies have been developed for the transdermal delivery of some important drugs. Transdermal route will always remain a lucrative area for drug delivery.The transdermal route of drug delivery has gained...
PLURIPOTENT STEM CELLS FOR VASCULAR DISEASE THERAPY
Vascular regeneration for ischemic disease represents an unmet clinical need. The ability to derive and expand homogenous populations of human vascular endothelial cells from either human embryonic stem (hES) cells or hu...
ORAL SUSTAINED RELEASE DRUG DELIVERY SYSTEM: AN OVERVIEW
In the recent years, focus on the development of oral controlled release drug delivery systems has increased. Oral ingestion has been the most convenient and commonly employed route of drug delivery. Indeed, for sustaine...
NANOBURRS: A NOVEL APPROACH IN THE TREATMENT OF CARDIOVASCULAR DISEASE
"Nanoburrs" are nanoparticles coated with a sticky protein that makes them cling onto artery walls while they slowly release drugs. Patients with narrowed arteries in which drug-eluting stents cannot be used, now can use...