Blood stream infections-prevalence in a tertiary care institute, Central India
Journal Title: Indian Journal of Microbiology Research - Year 2018, Vol 5, Issue 1
Abstract
nbspIntroduction Septicaemia is responsible for high morbidity and mortality in developing countries like India requiring prompt antimicrobial treatment for its proper managementAims and Objectives Detection of etiological agent from blood culture of suspected septicaemia patients and itrsquos antibiogramMaterial and Methods A total of 227 blood culture samples were collected in Microbiology Laboratory during 1 July2016 to 30 June2017 Etiologic agents were isolated using conventional as well as automated blood culture methods and their antibiotic susceptibility was determined using standard protocolResults Among clinically suspected septicemic patients 391718 were culture positive The most common organisms isolated were S aureus12 CONS8 Klebsiella pneumoniae5 and C albicans4 in decreasing order of their incidence 75 of S aureus were methicillin resistant All Gram positive organisms were sensitive to Glycopeptide antibiotics but showed variable resistance to other antibiotics Gram negative bacteria were multidrug resistant with high degree of resistance towards Quinolones Cephalosporins but a high sensitivity to Carbapenems Only one non fermenter was resistant to Carbapenems which was sensitive to ColistinConclusion The use of automation can be a useful tool for isolation of rare organisms The incidence of bacterial culture positivity is on the rise and fungal isolation is also common In this era where over the counter drugs are easily available drug abuse is difficult to control But having said that formulation of Hospital Antibiotic Policy and its strict implementation is the need of the hour which will eventually help us to control the menacing rise in antimicrobial resistancenbspnbspKeywords Escherichia coli Pseudomonas aeruginosa Staphylococcus aureusnbspnbsp
Authors and Affiliations
Prashant Meshram, Dilip Gedam, Nitin Ambhore, Rajesh Karyakarte
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