Canagliflozin – A Novel Oral Hyperglycemic Agent in The Fight Against Diabetic Mellitus
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 12
Abstract
Canagliflozin, is a first-in-class,oral hypoglycemic drug to be approved by US FDA, that acts through inhibition of sodium glucose co- transporters in the renal tubules, resulting in glucosuria. Clinical trials with canagliflozin have shown that it causes consistent dose-dependent reduction in HbA1c. The drug has a risk of causing genito-urinary infections& amputations in patients with diabetic foot ulcers. This article summarizes the current knowledge regardingcanagliflozin and its future perspectives in the treatment of type 2 diabetes mellitus
Authors and Affiliations
S. Melina. I. Sahay, DamalKandadai Sriram, Melvin George
Keywords
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- EP ID EP251473
- DOI 10.9790/0853-1612099296
- Views 85
- Downloads 0
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