Chronic obstructive pulmonary disease (COPD): influence of clinic-anamnestic, anthropometric and functional characteristics on serum α-1-anitrypsin (AAT) in stable patients
Journal Title: Медичні перспективи - Year 2018, Vol 23, Issue 3
Abstract
Aim of the study – to enhance the diagnostic and treatment tactics of stable COPD patients management at outpatient stage by studying the serum AAT. Data of 45 outpatients with COPD (GOLD I-IV) and 20 healthy persons were included into analysis. Sex, age, height, weight, body mass index (BMI), smoking status were assessed. Lung function and serum AAT were measured. These results suggest that sex, age, height, weight, BMI do not influence on serum AAT both in stable COPD patients and healthy persons. Serum AAT statistically significant negatively correlate with airways obstruction degree in stable COPD patients. Significant moderate negative correlation between serum AAT and number of exacerbation during last year was found in stable COPD patients. This finding allows to suggest that serum AAT could be used as an indicator for COPD prognosis.
Authors and Affiliations
K. Yu. Gashynova
Keywords
Related Articles
- EP ID EP435861
- DOI 10.26641/2307-0404.2018.3(part1).142334
- Views 76
- Downloads 0
Prevention of complications after surgical treatment of colpocystocele
78 women with the diagnosis of cystocele were examined. The average age of the examined women was 61.5±9.3 years, the age of women in the control group was 56.7±1.8 years (p>0.05). The results of postoperative treatment...
Генотип цитохрому-450 2C9 у хворих на туберкульоз
Целью данной работы было исследование полиморфизма генотипа цитохрома-450 (CYP) 2С9 CYP2С9 на юге Украины у больных туберкулезом и сравнение с аналогичными показателями контрольной группы на примере Одесского региона. С...
Clinical and epidemiological features of chronic pancreatitis course associated with atherosclerosis
The article describes and analyzes dyslipidemic disorders, the degree of pancreatic external secretion insufficiency in patients with chronic pancreatitis. The purpose of our study is to study the changes in the blood li...
Dynamics of cumulating of metronidazole in the gut wall on a model of mechanical ileus
The frequency of acute intestinal obstruction in relation to urgent surgical diseases in Ukraine remains high and reaches 3.8-6%. In the postoperative period, such patients develop a high number of severe purulent-septic...
Особливості біоелектричної активності серця у дітей з хронічним пієлонефритом
Целью работы было определение особенностей биоэлектрической активности сердца у детей в зависимости от продолжительности хронического пиелонефрита и наличия сопутствующих хронических очагов инфекции. Проведен анализ резу...