Clinical and epidemiological features of chronic pancreatitis course associated with atherosclerosis

Journal Title: Медичні перспективи - Year 2018, Vol 23, Issue 3

Abstract

The article describes and analyzes dyslipidemic disorders, the degree of pancreatic external secretion insufficiency in patients with chronic pancreatitis. The purpose of our study is to study the changes in the blood lipid profile in patients with chronic pancreatitis depending on the degree of pancreatic external secretion insufficiency in residents of the city and villages. We carried out the 13C-mixed triglyceride respiratory test (13C-MTRT) and the 13C-amylase respiratory test (13C-ART) to detect the pancreatic external secretion insufficiency (PESI). Changes in the blood lipid profile were based on the violations in the lipidogram (determination of total blood cholesterol level (TC), triglycerides (TG), high density lipoproteins (HDL), and low density lipoproteins (LDL), atherogenicity coefficient (CA)). All examined patients with combination of chronic pancreatitis (CP) and athe¬rosclerosis have lipid metabolism disorders, but the changes in the city residents are more significant as compared with the rural population. It was also found that the most pronounced violation of the PESI was observed in patients with CP and lipid metabolism disorders, who were residents of the city. In these patients, during the 13C- MTRT, the maximum concentration of 13СО2 between 150 and 210 minutes were at the level of 4.9±0.7%; total concentration of 13СО2 at the end of the study (360 min.) – 17,1±0,3% and were statistically significant in comparison with the control group.

Authors and Affiliations

E. S. Sirchak, S. M. Opalenyk

Keywords

Related Articles

Neurochemical and behavioral processes in gerontogenesis in conditions of experimental hyperglycemia

Many researchers are increasingly interested in the relation between diabetes and diabetic encephalopathy. At the moment, there are various experiments where this issue is considered. But despite prolonged studying, it i...

Clinical and statistical aspects of gastrointestinal bleeding course in patients with cardiovascular system pathology

We have collected, processed and analyzed the results of treatment of 329 patients with gastrointestinal bleedings in which the course of the underlying disease is aggravated by the pathology of the cardiovascular system...

Неспецифический гнойный остеомиелит позвоночника

Останнім часом в Україні відзначається тенденція до зростання захворюваності на гнійний остеомієліт хребта. Основними факторами, що сприяють зростанню захворюваності, є збільшення частки імуноскомпрометованого населення...

Features of the mental status of patients with community-acquired pneumonia, combined with a chronic pathology of the hepatobiliary system of non-viral genesis

The aim was to study the characteristics of mental status of patients with community-acquired pneumonia (CAP), combined with a chronic pathology of the hepatobiliary system of non-viral genesis. We observed 165 patients...

Peculiarities of toxicodynamics and hazard assessment of pymetrozine,a new insecticide

It is well known that despite an actual efficiency pesticides can have a negative impact on humans, animals and the environment. So, new pesticides must be regulated at the stage of their registration in order to prevent...

Download PDF file
  • EP ID EP436045
  • DOI 10.26641/2307-0404.2018.3(part1).142373
  • Views 98
  • Downloads 0

How To Cite

E. S. Sirchak, S. M. Opalenyk (2018). Clinical and epidemiological features of chronic pancreatitis course associated with atherosclerosis. Медичні перспективи, 23(3), 188-192. https://europub.co.uk./articles/-A-436045