Circulation of Dengue Virus -2 in Chennai-2014, India.
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 3
Abstract
Background:Dengue infection is the most rapidly emerging serious health problem in Tamil Nadu. We report emergence of the dengue 2- strain in Chennai, Tamil Nadu, India. Background: This study aims to describe the molecular characterization of circulating DENV serotypes between Dec 2013-Jan 2014 by identifying dengue specific NS1, IgM and IgG antibodies by NS1 , IgM&IgG capture Enzyme Linked Immuno Sorbent Assay (ELISA) using PanBio kit( NS1 &IgG) andIgM antibody capture ELISA by using NIV kit. Results:A total of 304 fever cases with clinical signs and symptoms suggestive of dengue were tested in Chennai district. Serodiagnosis revealed that 29 (9.5%) were positive for IgM antibodies, 23 (7.6%) were dengue IgG antibodies positive and 3 (1 %) for IgM antibodies only. RT-PCRtest revealed circulation of dengue 2 serotypes. Conclusion:These results show the reemergence of dengue 2 sero type in Chennai, Tamil Nadu. There is no literature evidence for Dengue 2 virus circulation in Chennai since 2001. The study of various serotypes in the dengue endemic region may act as predictive marker to define the range of manifestation in future.
Authors and Affiliations
SenthilRaja Ramalingam, Karupannan2 , . , Padmapriya , Padmanaban1, Senthilkumar Vijayan1 ,, Khallefathullah Sheriff1 ,, Gunasekaran Palani, Kaveri Krishnasamy*
Keywords
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- EP ID EP384858
- DOI 10.9790/3008-1103040106
- Views 84
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