Clinical Efficacy of Placentrex Injection in Pelvic Inflammatory Disease
Journal Title: Indian Journal of Obstetrics and Gynecology Research - Year 2016, Vol 3, Issue 1
Abstract
Pelvic inflammatory disease (PID) is one of the most frequent infections seen in reproductive age group and is associated with major clinical and pelvic health problem. It is Infection & inflammation of upper genital tract organs typically involving fallopian tubes, ovaries & surrounding structures. PID is polymicrobial in nature and is associated with different etiological agents. Clinical presentations may vary from mild to severe. No specific signs and symptoms are pathognomic of PID. Laboratory tests are also poor predictors of PID. There may be subclinical symptoms and patient later may present with infertility. CDC recommends treatment for even mild cases of PID. Therapeutic goal in management of PID is to prevent chronic residual disease. Failure of antibiotic therapy to prevent sequelae of salpingitis reflects the emphasis of additional therapy along with antibiotics. Placentrex is a drug containing Peptides (FNP-III, CRF), Nucleotides (PDRN) & Glutamate and is derived from an extract of fresh term, healthy, human placenta. It has significant anti inflammatory effect involving chemical mediators of immunological response. Effect of placentrex is well documented in wound healing1 and in treatment of burns and radiation effects 2. It has been recommended for prescription for PID but there is not much data in literature regarding the efficacy in PID. So we conducted a trial to find efficacy of placentrex in comparision with azithromycin for the treatment of PID.
Authors and Affiliations
Prameela Prameela, Kavya D Sharma
Keywords
Related Articles
- EP ID EP241136
- DOI -
- Views 109
- Downloads 0
Endoscopic surgical treatment of isthmocele and it’s probale link with endometriosis. A 3-years retrospective review of combined laparoscopic and hysteroscopic surgery
The aim is to share our experience on the efficacy of combined laparoscopic and hysteroscopic surgical treatment of isthmocele and the possible link with endometriosis 28 patients with isthmocele who underwent combined l...
Diagnostic dilemmas in ectopic pregnancy
Aim of the study: To find out the atypical presentations of ectopic pregnancy that had lead to delay in diagnosing cases of ectopic pregnancy leading to increased morbidity and sometimes mortality. Study design: It is a...
Intracervical dinoprostone versus sublingual misoprostol for preinduction ripening of cervix
Objective: To compare the efficacy of intracervical dinoprostone and sublingual misoprostol in preinduction cervical ripening. Study design: This prospective observational study was performed on 410 women with medical or...
Fetomaternal Outcome in Acute Viral Hepatitis
Introduction: Viral hepatitis is one of the commonest causes of jaundice in pregnancy. Hepatitis E viral (HEV) infection is associated with major catastrophes in pregnancy with high maternal and foetal mortality rate. Ob...
A comparative study of subcuticular versus three mattress sutures for pfannenstiel skin closure in obstetrics and gynaecological surgeries
Objective: To compare application of subcuticular sutures, with three mattress sutures for pfannenstiel incision closure. Materials and Methods: Cross sectional study comparing subcuticular sutures to three mattress sutu...