Comparative Study between the Effects of 4% Lignocaine Solution through Endotracheal Tube Cuff and 1.5 mg/kg of Intravenous 2% Lignocaine on Coughing and Hemodynamics During Extubation in Neurosurgical Patients
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 5, Issue 11
Abstract
Aim: A prospective, randomized, double-blind trial was performed to compare the effects of 4% endotracheal tube cuff lignocaine and 1.5 mg/kg intravenous lignocaine on coughing and hemodynamics during extubation in patients undergoing neurosurgical procedures. Methods: Group A (n = 50) patients received 4% lignocaine into endotracheal tube cuff after intubation and Group B (n = 50) patients received intravenous lignocaine 2% at 1.5 mg/kg before extubation. Coughing was assessed by the scale of 3 at the time of extubation, 0–2 min, 2–4 min, and 4–8 min post-extubation. Hemodynamic parameters were recorded at 1 min, 2 min, 5 min, and 10 min and were compared with baseline values. Results: Comparison of hemodynamic variables, incidence, and severity of cough at emergence was analyzed using unpaired t-test. The incidence and severity of cough were less in Group A when compared to Group B. There was no significant difference in hemodynamic variables in between the groups. Conclusion: Intracuff 4% lignocaine was found to be superior to 2% intravenous lignocaine in suppressing cough during emergence.
Authors and Affiliations
B V Mahesh Babu, Saladi Aruna Kumari, B Soubhagya Lakshmi
Keywords
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