Comparative study of efficacy of topical dexamethasone 0.1% with difluprednate 0.05% in post-operative small incision cataract surgery
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2018, Vol 4, Issue 3
Abstract
Introduction Postoperative ocular inflammation is a common occurrence following cataract surgery Corticosteroids have been used to treat ocular inflammation however they carry a risk of side effects particularly an increase in intra ocular pressure IOP Previous studies have proved that difluprednate is more efficacious compared to dexamethasone Hence this study was undertaken to compare the efficacy of difluprednate ophthalmic emulsion 005 and dexamethasone 01 in postoperative management after small incision cataract surgeryMaterials and Methods A total 200 patients were selected as per inclusion criteria and equally divided between difluprednate and dexamethasone groups Dexamethasone 01 or difluprednate005 was prescribed post operatively following small incision cataract surgery Patients were examined on postoperative day 1 7 15 and 30 for anterior segment by slitlamp examination and side effects IOP was measured in both the groups on day 30Results In our observation both drugs were efficient in the reduction of anterior chamber cells and flare with difluprednate being more rapid Corneal edema was reduced equally by both the drugs at all observation periods There was no clinically significant IOP elevation in both difluprednate and dexamethsone group Difluprednate was found to be more effective in controlling pain compared to dexamethasoneConclusion As per present study both difluprednate ophthalmic emulsion 005 eye drops and dexamethasone 01 eye drops were equally effective in reducing post cataract surgery inflammation Hence difluprednate emulsion 005 can be used in postoperative management after cataract surgery nonetheless further clinical trials with long follow up period are required Keywords Cataract surgery Dexamethasone Difluprednate Dose uniformity Ocular inflammation Opthalmic emulsion
Authors and Affiliations
Rajashree Reddy, Ashwini Patil
Keywords
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- EP ID EP474259
- DOI 10.18231/2395-1451.2018.0076
- Views 104
- Downloads 0
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