Comparative Study of Outcome of Axial Continuous-Flow HeartMate II LVAD Implantation with Fully Magnetically Levitated Centrifugal Continuous-Flow HeartMate 3 LVAD for the Treatment of Advanced Heart Failure
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 5
Abstract
Introduction: Left ventricular assist devices (LVAD) or assist systems, increase the rate of survival and improve quality of life among patients with advanced heart failure. So this study was done to compare the outcome and adverse events of our HeartMate II left ventricular assist device (HM II LVAD) implantation with recent published report of novel HeartMate 3 (HM 3) performance from CE Mark and MOMENTUM 3 trials. Material and Methods: We retrospectively analysed our data of 44 eligible patients out of 58 who had HM II LVAD implantation. These data were compared with HM 3 cohort outcome from MOMENTUM 3 and CE mark trial. Results: Our 44 HM II patients comprised of 23 (52%) Ischemic Cardiomyopathy (ICM) and 21(48%) non-Ischemic Cardiomyopathy (NICM). 78% of ICM and 67% of NICM group were male with average age of 63.7 ± 6.8 years and 53.9 ±16.3 respectively. 43.5% of ICM and 9.5% of NICM (p=0.012) had previous sternotomy. 78% of ICM and 67% of NICM (p=NS) were done as bridge to transplant; 22% of ICM and 33% of NICM (p=NS) were for destination therapy. 17% of ICM and 0% of NICM (p =0.06) were reported to have 30-day mortality. Conclusion: ICM etiology was an independent predictor of mortality in our HM II cohorts. Our Pump thrombosis and mortality results were comparable to HM 3 cohort outcome results of the CE Mark trial and MOMENTUM 3 trial.
Authors and Affiliations
Sanjay Kumar, Abeel A. Mangi
Keywords
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