Comparison of BD Affirm VPIII with Gram and liquid-based cytology for diagnosis of bacterial vaginoses, candidiasis and Trichomonas
Journal Title: Clinical and Experimental Obstetrics & Gynecology - Year 2019, Vol 46, Issue 1
Abstract
Background: Vaginitis require complementary methods for adequate diagnosis. New technologies have been developed and need to be compared with those already established. Aims: The objective of this study was to compare the results of BD Affirm VPIII with Gram smear and liquid-based cytology in diagnosis of bacterial vaginosis (BV), Candida sp, and Trichomonas vaginalis. Materials and Methods: A cross-sectional study was performed in 90 women from March to November 2016 in a gynecology clinic in a Brazilian city, Fortaleza. The Affirm test, Gram, and Surepath were performed in vaginal samples. Categorical data was evaluated for sensibility, specificity, and predictive values. To quantify the agreement, the Kappa index was utilized. Results: Comparing Affirm test with Gram stain for BV and Surepath, the sensitivity was 83.3% and 27.8%, and the specificity was 62.2% and 95.5%, respectively. The Kappa index was 0.204 to Gram and 0.247 to Surepath. For Candida sp comparing with Gram and Surepath, the sensitivity was 61.1% and 56.3%, and the specificity was 93.3% and 100%, respectively. The Kappa index was 0.585 to Gram and 0.677 to Surepahth. Conclusion: The Affirm test had a fair concordance with Gram and Surepath in the diagnosis of BV, and substantial agreement in the diagnosis of Candida.
Authors and Affiliations
J. Eleutério Junior, R. M. Nunes Eleutério, A. B. Gordiano Vasconcelos Valente, F. Soares Queiroz, A. K. Silveira Gonçalves, P. C. Giraldo
Keywords
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- EP ID EP618498
- DOI 10.12891/ceog4369.2019
- Views 48
- Downloads 0
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