Comparison of Del Nido and St. Thomas Cardioplegia in adult cardiac surgery
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 11
Abstract
Introduction: Del Nido (DN) cardioplegia was invented specially for pediatric cardiac surgery in the 1990s and has longer ischaemic time (less redosing) than ST Thomas cardioplegia (ST). Aim of Study: To evaluate the safety/efficacy of DN over ST for adult cardiac surgery. Materials and Methods: The study was conducted among 100 adult patients who underwent CABG/MVR/DVR/AVR. Patients were divided in 2 groups: group 1- who received DN cardioplegia (n=50) and group 2- who received ST cardioplegia (n=50). Cross clamp time (X clamp time), cardiopulmonary bypass time (CPB time), ionotropic support and post cross clamp defibrillation rates were analysed. Results: The aortic cross clamp and bypass times were shorter with DN than ST (91.94±34.16 vs 106.44±32.63 and 126.26±37.50 vs 139.84±37.84, p value <0.05 respectively). ST group needed higher ionotropic support than DN group (14.62±3.83 vs 11.42±2.84, p value< 0.05). DN group showed significant reduction in Post X clamp defibrillation rate than ST group (5 vs 15, p value<0.05). Conclusion: DN reduces X clamp and CPB time over ST , and less ionotropic support and post X clamp removal defibrillation is required when using DN in adult cardiac surgery.
Authors and Affiliations
Dr Sumanta Das
Keywords
Related Articles
- EP ID EP489972
- DOI -
- Views 58
- Downloads 0
Evaluation of Cardiovascular Status in Thyroid Disorders
Context: Thyroid disorders (hypothyroidism and hyperthyroidism) are associated with clinically significant cardiovascular changes. In the present study, patients with various types of thyroid disorders examined clinicall...
A Comparative Study of Prostaglandins (Intravaginal PGE1& Intracervical PGE2) with Oxytocin Infusion for Induction of Labour
Induction of labour is the deliberate initiation of labour before spontaneous onset anytime after the period of viability with the aim of delivery per vagina as a matter of urgency either for the foetus or the mother or...
Thrombocytopenia and Prolonged Prothrombin Time in Neonatal Septicemia
Septicemia in neonates refers to generalized bacterial infection documented by positive blood culture in the first 28days of life and is one of the leading causes of neonatal mortality in sub-Sahara Africa. Thrombocytope...
The Emergence and Importance of Moraxella Catarrhalis as Human Respiratory Tract Pathogen and its Antibiogram
Background: Moraxella catarrhalis is a Gram-negative diplococcus, commonly found as a normal flora in the human upper respiratory tract. Recently, M. catarrhalis has emerged as an important human pathogen in respiratory...
Clinical and Biochemical Profile of Neonates with Hyperbilirubinemia in a Tertiary Care Center
Background: Neonatal hyperbilirubinemia, though of common occurrence, is a significant medical condition not only because of its impact on hospital discharge but more importantly because of its potential to cause serious...