Comparison of Sputum Culture and Protected Brush Biopsy Specimen Culture through Fibreoptic Bronchoscope in Lower Respiratory Tract Infections - A Hospital based Study
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 7
Abstract
Introduction: The sputum remains the most common diagnostic specimen for isolating the causative microbes from the infected lung in spite of its proved poor yield of the true pathogens and too often findings of false pathogens. The sputum from the lung tissue passes to bronchi, trachea, larynx, hypopharynx, pharynx, nasopharynx and oral cavity where it is subsequently contaminated by addition of secretions from respective sites. Various methods have been evolved to reduce the method of contamination of sputum in order to improve the culture results. The aim of present study is to compare prebroncoscopic sputum culture results with those of protected brush biopsy specimens obtained by fiberoptic bronchoscope in lower respiratory tract infections. Materials and methods: The present study was conducted on 40 cases of lower respiratory tract infections. All the patients were admitted to Chest and T.B.Hospital attached to Govt. Medical College, Patiala. The patients showed features of chronic bronchitis, bronchiectasis and pneumonias both clinically and radiographically were included in the study. The written consent of the patients was obtained and various investigations like sputum for A.F.B, Hb, TLC, DLC, urine, Blood urea and fasting blood sugar was carried out. The clinical information was recorded and clinical examination performed. Sputum samples and brush biopsy samples were obtained by bronchoscope and cultures. The results were arranged in a tabulated form and analysed. Result: Out of these 40 patients 36 patients (90%) were suffering from bronchiectasis, 3 patients (7.5%) were of pneumonia and 1 patient (2.5%) of chronic bronchitis. Table- 1 shows that in 39 cases, bronchoscopy was done by transnasal approach and in 1 patient it was done by transoral approach. Conclusion: It can be concluded from the above study that fibreoptic bronchoscopic use with protected brush specimen reduces the incidence of contamination and gives better results for anaerobic infections of lower respiratory tract as compared to sputum culture.
Authors and Affiliations
Kulbir Singh, S. K Bansal, Sashi Kanta, Parminder Pal
Keywords
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