COMPARISON OF THYROID PROFILE IN PREMENOPAUSAL AND POSTMENOPAUSAL WOMEN
Journal Title: International Journal of Basic and Applied Physiology - Year 2017, Vol 6, Issue 1
Abstract
Background and Objectives: Diseases of the thyroid gland are among the most abundant disorders worldwide second only to diabetes. Normal levels of thyroid hormone are essential for normal reproductive behavior and physiology. Onset increases with age and it is estimated that 26% of premenopausal and menopausal women are diagnosed with thyroid disease. Thyroid disorders are more common in women than men. Methods: This study consists of two groups. The control group included 50 premenopausal women with the age 40 years or more. The study group included 50 postmenopausal women with duration not more than 5 years of menopause. Any female who had not had menstruation for a minimum duration of 1 year was considered as postmenopausal. Different thyroid function tests (Serum TSH, Serum total T3, Serum total T4) were done in both the age groups to determine thyroid status. Results: Comparison of thyroid profile was done between premenopausal & postmenopausal women. Data analysis was done by Z test. p value <0.05 considered as significant. Statistical analysis was done using SPSS 20.0 software. 18% of postmenopausal women had high Serum TSH, low S. T4, low S. T3 levels suggestive of hypothyroidism & 6% of postmenopausal had low S.TSH, high S.T4, S.T3 values suggestive of hyperthyroidism. Conclusion: We conclude that it is advisable to include thyroid screening as routine investigation in the women presenting with menopausal symptoms for the first time. Those with abnormal thyroid parameters should be treated accordingly. Those with borderline shift in thyroid parameters should be periodically screened for the same. Evaluating serum TSH alone would be sufficient to evaluate thyroid status. This simple measure would provide timely diagnosis of thyroid disorders at the time of menopause if any.
Authors and Affiliations
Nilay kapadia, Neeta Mehta
Keywords
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