Correlation of Agaston Score in Obstructive and Non-obstructive Coronary Artery Disease following ST segment elevation Myocardial Infarction
Journal Title: Stanley Medical Journal - Year 2016, Vol 3, Issue 3
Abstract
The purpose of the study is to compare coronary artery calcium score in patients with Obstructive & Non obstructive coronary artery disease CAD and to compare coronary artery calcium score in patients with single & multivessel disease and between infarct related artery & other vessels in multivessel disease.The study is a prospective observational non interventional study involving 100 patients after the treatment of ST-segment elevation myocardial infarction. Based on coronary angiogram findings the study population is categorized into study group with obstructive coronary artery disease and non obstructive coronary artery disease. The assessment of CAC score was done with no knowledge about the CAG lesions of the patients concerned. Statistical analysis used: Chi-square test, Mann Whitney U Wilcox on Rank Sum test, Correlation coefficient methods & Multiple regression analysis and p values were found Our study showed poor sensitivity, specificity, predictive values and likelihood ratios in using Agatston score to differentiate Obstructive CAD from Nonobstructive CAD. The p values show no statistical significance. MDCT derived Agatston score shows poor correlation in differentiating the obstructive and non obstructive coronary artery disease following STEMI, not useful to identity infarct related artery and no linear correlation between CAC score and the number of vessel involvement.
Authors and Affiliations
Chezhian J, Manimekala E, Geetha K, Kailasanathan N
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