Correlation of bleeding time and clotting time in different phases of menstrual cycle
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 10
Abstract
Background: Changes in the levels of female sex hormones during the menstrual cycle are known to affect the coagulation cascade by producing parallel changes in the prothrombotic tendency and the fibrinolytic activity of healthy women. Aims and Objectives: The aims of the study was to access the changes in bleeding time (BT) and clotting time (CT) during different phases of menstruation. Materials and Methods: Study was conducted in the Department of Physiology, TMMC and RC over a period of 1 year. A group of 40 females between the age group of 18–25 years having normal menstrual cycle were selected. Females with hormonal disorders, taking hormonal medication having hematological, gynecological or any chronic disorder were excluded. There BT and CT were accessed in four phases of menstrual cycle, i.e., menstrual phase, proliferative phase, ovulatory phase, and secretory phase. Data were analyzed using SPSS software. Results: The mean BT shows a significant difference (P = 0.001). BT was least around the Ovulatory Phase or mid-cycle, and it increases during secretory phase. CT was least around ovulatory or mid-cycle, and it increases during secretory phase. However, the difference of CT in different phases was not statistically significant. Conclusion: The present study indicates that primary and secondary hemostatic mechanism activities are higher in the follicular and ovulatory phase than remaining phases. Hence, optimal hemostatic testing time must be done in menstrual and early follicular phase.
Authors and Affiliations
Shivani Prajapati, Ritu Adhana, Anjali Verma
Keywords
Related Articles
- EP ID EP491753
- DOI 10.5455/njppp.2018.8.0619707062018
- Views 78
- Downloads 0
A study of waist circumference, hip-waist ratio as markers of Type 2 diabetes mellitus in male population of North Karnataka
Background: Type 2 diabetes mellitus belongs to a group of diseases labeled as “lifestyle diseases” and is on the rise in Asians, especially Indians. It is estimated that by 2030, the number of people with diabetes will...
Electromyogram, hand grip strength and time to fatigue in matched samples of vegetarians and non-vegetarians
Background: Nutritional content of diet of vegetarian (V) and non-vegetarian (NV) differs in terms of food composition, and vegetarian diets are often low in protein, probably causing a difference in body composition, st...
Effects of chronic ingestion of Bisphenol A on gut contractility in rats
Background: Bisphenol A (BPA) is a plastic toxin widely used in manufacturing of plastic containers. It is known to produce a variety of toxic effects on body functions including reproduction, metabolism, and development...
Role of serum uric acid and nitric oxide in the diagnosis of Type 2 diabetes mellitus - A case–control study
Background: The studies have reported that high serum uric acid (UA) and low nitric oxide (NO) levels are strongly associated with prevalent health conditions such as obesity, insulin resistance, metabolic syndrome, diab...
Effect of Hordeum vulgare, Moringa oleifera, and Vitex negundo extracts on the hippocampus and memory of Mus musculus
Background: Herbal medicines such as Hordeum vulgare, Moringa oleifera, and Vitex negundo are widely recognized around the world as dietary supplements, remedy for ailments, and bodily sustenance. Moreover, studies have...