Correlation of clinical variables with hypoxic ischemic encephalopathy stages
Journal Title: Medpulse International Journal of Pediatrics - Year 2018, Vol 8, Issue 2
Abstract
Background: The fetus with significant hypoxia episode is at risk of developing HIE and it may result in neonatal death or permanent motor and mental disability. Various epidemiologic studies have identified adverse sociodemographic factors, maternal conditions, and antenatal complications in association with HIE. Aim: To correlate clinical variables with hypoxic ischemic encephalopathy stages. Material and Methods:The study was conducted on 150 asphyxiated babies admitted to NICU with Apgar score of 6 or less at 5 minutes of birth. Intrapartum signs of fetal distress, as indicated by non-reassuring non-stress test on continuous electronic fetal monitoring and by thick meconium stained amniotic fluid. HIE was classified into mild, moderate, or severe HIE, as defined by Sarnat and Sarnat staging.Results: The maternal history, gestational age and mode of delivery were found to be not significant and do not correlate with the severity of HIE. A non-reactive non-stress test (NST) and thick meconium staining of the liquor found to be statistically significant.Conclusion: Consideration of the clinical variables during diagnosis and treatment of cases with HIE can improve the objectivity of the assessment and monitoring of newborns and the early start of treatment.
Authors and Affiliations
Priyanka Akka, Pallavi .
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