CURRENT STATUS OF EPILEPSY IN MALAYSIA AND WAY AHEAD

Abstract

Epilepsy is the third most common neurological disorder, following stroke and Alzheimer’s disease with the highest frequency of newly identified cases occurring among children and adults. About 50 million people worldwide have epilepsy, and nearly 80% of epilepsy occur in developing countries including Malaysia. In Malaysia, epilepsy is still a highly misunderstood and a number of studies explored the poor understanding of the illness. Epilepsy patients have the serious impact on quality of life. Both individuals and families of the patients have an appalling experience. Another factor is cost of AEDs which is very high. It is a burden for both patients and their families to meet the costs. There is a significant need persists to develop an accessible, cost effective, efficacious and less toxic antiepileptic drugs. Natural products used in traditional herbal medicine can be an important source for the search of novel anti-epileptogenic compounds. A number of plants used in traditional medicine have shown to possess anticonvulsant activity. Malaysia is rich in medicinal plants. Attempts have been made in the past to explore the effectiveness of some medicinal plants for the treatment of epilepsy, but the rationale for selection of plants was not justifiable and hence they failed to get a hit. Some of the Malaysian plants are used by traditional healers in the treatment of epilepsy, but their therapeutic effectiveness is not being scientifically explored. This review focused to enlighten the status of epilepsy and research required for the Malaysian medicinal plants for the treatment of epilepsy. 

Authors and Affiliations

Alina Arulsamy, Bey Hing Goh, Mohd Farooq Shaikh

Keywords

Related Articles

A SIMPLE (HPLC–UV) METHOD FOR THE QUANTIFICATION OF COLCHICINE IN BULK AND ETHOSOMAL GEL NANO-FORMULATION AND ITS VALIDATION

Objective: To develop and validate a stability-indicating reversed phase high-performance liquid chromatography (RP-HPLC) method for the determination of colchicine in bulk and ethosomal gel nano-formulation.Methods: The...

SYNTHESIS AND DOCKING STUDIES OF 2-(NITROOXY)-ETHYL-2-(SUBSTITUTED-2,5-DIPHENYL-OXAZOLE)-ACETATE AS ANTI-INFLAMMATORY AGENTS WITH ANALGESIC AND NITRIC OXIDE RELEASING PROPERTIES

Objective: The objective of the reported study was to develop new chemical entities as potential anti-inflammatory agents with analgesic and nitric oxide releasing properties.Methods: The compounds were designed with the...

DEVELOPMENT AND IN VIVO EVALUATION OF TOLCAPONE CONTROLLED RELEASE TRILAYER MATRIX TABLETS BY GEOMATRIX TECHNOLOGY

Objective: The present study was aimed to develop once-daily controlled release tri-layer matrix tablets of tolcapone, to achieve zero-order drug release for sustained plasma concentration by Geomatrix.Methods: Tolcapone...

METHOD DEVELOPMENT AND VALIDATION FOR THE QUANTITATIVE ESTIMATION OF ACAMPROSATE CALCIUM IN TABLETS USING RP-HPLC

Objective: To develop an accurate, precise and linear Reverse Phase High Performance Liquid Chromatographic (RP-HPLC) method and validate as per ICH guidelines for the quantitative estimation of Acamprosate calcium (333...

ANTIFEEDANT EFFECTS OF VITEX NEGUNDO L. LEAF EXTRACTS ON THE STORED PRODUCT PEST, TRIBOLIUM CASTANEUM H. (COLEOPTERA: TENEBRIONIDAE)

Objective: This study aims to evaluate the nutritional and feeding deterrence indices of Tribolium castaneum adults caused by petroleum ether and methanol extracts of Vitex negundo.Methods: A modified method of flour dis...

Download PDF file
  • EP ID EP579148
  • DOI -
  • Views 78
  • Downloads 0

How To Cite

Alina Arulsamy, Bey Hing Goh, Mohd Farooq Shaikh (2015). CURRENT STATUS OF EPILEPSY IN MALAYSIA AND WAY AHEAD. International Journal of Pharmacy and Pharmaceutical Sciences, 7(1), 2-5. https://europub.co.uk./articles/-A-579148