Cutaneous Manifestations of Brucellosis
Journal Title: Macedonian Journal of Medical Sciences (MJMS) - Year 2010, Vol 3, Issue 3
Abstract
Aim. To present and compare 10-year clinical experience of human brucellosis in Republic of Macedonia with data presented in the literature about the frequency of cutaneous manifestations of brucellosis. To estimate the percent of underdiagnosed / misdiagnosed skin lesions related to brucellosis and to raise awareness of cutaneous manifestations of brucellosis in our clinical practice. Methods. Clinical records and experience of the Infectious Diseases Clinic and Dermatology Clinic, Faculty of Medicine, Skopje, and a review of the recent literature data about cutaneous manifestations of brucellosis relevant for dermatologists, infectologists and general practitioners. Results. Cutaneous manifestations or complications have been reported rarely, less than 5% (3.8 % - 17 %) in different published studies. A variety of skin lesions have been reported in patients with brucellosis, including rashes (25%), nodules, papules, erythema nodosum (25%), eczematous lesions (12.5%), psoriasiform lesions (12.5%), petechiae, purpura and others. Conclusion. Human brucellosis should always be in the differential diagnosis of a patient with rash and fever. Cutaneous findings may be useful in diagnosing brucellosis in persons who live in endemic regions. Early diagnosis and timely initiation of proper antibiotic treatment are of major importance for the effective cure and prevention of complications of the disease. General practitioners and clinicians, especially dermatologists, have to be more alert in clinical recognition and laboratory verification of brucellosis as an important public health problem.
Authors and Affiliations
Margareta Balabanova-Stefanova| University Clinic of Dermatology, Medical Faculty, Skopje, Republic of Macedonia, Agron Starova| University Clinic of Dermatology, Medical Faculty, Skopje, Republic of Macedonia, Irina Arsovska-Bezhoska| University Clinic of Dermatology, Medical Faculty, Skopje, Republic of Macedonia
Cutaneous Manifestations of Brucellosis
Aim. To present and compare 10-year clinical experience of human brucellosis in Republic of Macedonia with data presented in the literature about the frequency of cutaneous manifestations of brucellosis. To estimate th...
Response to Comment on the Publication: Lazarevik V, Kasapinov B. Medical Doctors’ Attitudes towards Pay-ForReporting in Macedonia: A Web-Based Cross-Sectional Survey. Maced J Med Sci. 2012;5(4):437-443
In our view, this letter does not argue with the substance of our study, but with the title that can be debated endlessly. Vladimir Lazarevik is not involved in the creation of any health care policy since August 2008....
Antioxidant Effects of Nigella Sativa in the Treatment of Experimentally Induced Rhinosinusitis
Aim. The objective of this study was to investigate the effect of Nigella sativa (NS) in experimental bacterial rhinosinusitis. Material and Methods. Bacterial rhinosinusitis was induced with Staphylococcus aureus. Rab...
Influence of Type 2 Diabetes and the Sex on the Occurrence of Sub-Clinic Left-Ventricular Diastolic Dysfunction of the Heart
Aims: To test the hypothesis that: the potential of type 2 diabetes, in precipitation of the sub clinical left ventricular diastolic dysfunction at the female sex, in absence of high blood pressure disease, coronary di...
HCV-Core Region: Its Significance in HCV-Genotyping and Type Dependent Genomic Expression
Present study reports the standardization and use of polymerase chain reaction (PCR) followed by RFLP (PCR-RFLP) implicating HCV-core as a target region and its comparison with PCR-RFLP based on the use of 5'NCR for HC...