CYTOPROTECTIVE EFFECT OF NOVEL 4-THIAZOLIDINONE DERIVATIVES AGAINST STRESS CONDITIONS IN SMALL INTESTINE OF RATS
Journal Title: Праці Наукового товариства ім. Шевченка - Year 2017, Vol 49, Issue
Abstract
Stress affects the integrity of the intestinal barrier and increases it permeability, reduces mucosal blood fl ow due to catecholamines driven vasoconstriction, leading to hypoxia and nitroso-oxidative processes. The experimental data demonstrates that H2S can exert protective actions against injury induced by various factors. The purpose of this investigation was to explore the role of 4-thiazolidinone-based derivatives as a novel donors of H2S in promoting the resolution of infl ammation in small intestine.
Authors and Affiliations
I. Ilkiv, R. Lesyk, O. Ya. Sklyarov
Keywords
Related Articles
- EP ID EP316878
- DOI -
- Views 84
- Downloads 0
LIFE CREDO - SERVING SCIENCE
This year on the 10th of March, Dmytro Deonysovych Zerbino, clinical pathologist, who started to work at Lviv University in 1966, celebrated his 90th birthday. D.D. Zerbino - doctor of medical sciences (1965), professor...
РІВЕНЬ ФАКТОРА НЕКРОЗУ ПУХЛИНИ АЛЬФА ПРИ ГОСТРОМУ ХОЛЕЦИСТИТІ, ГОСТРОМУ АПЕНДИЦИТІ ТА ЧЕРЕВНОМУ ТУБЕРКУЛЬОЗІ В ЗАЛЕЖНОСТІ ВІД ТИПУ АДАПТАЦІЙНОЇ РЕАКЦІЇ
РІВЕНЬ ФАКТОРА НЕКРОЗУ ПУХЛИНИ АЛЬФА ПРИ ГОСТРОМУ ХОЛЕЦИСТИТІ, ГОСТРОМУ АПЕНДИЦИТІ ТА ЧЕРЕВНОМУ ТУБЕРКУЛЬОЗІ В ЗАЛЕЖНОСТІ ВІД ТИПУ АДАПТАЦІЙНОЇ РЕАКЦІЇ
TREATMENT OF ACUTE PANCREATITIS: PROGRESSING FROM A DIAGNOSIS OF PANCREATITIS AND ITS FORMS TO ITS COMPLICATIONS
This article presents an analysis of the literature concerning approaches of the surgical treatment of acute pancreatitis. The in-depth study of the problem of acute pancreatitis and the development of management tactics...
DO GLYASER’S FISSURE IS TRULY GLYASER’S FISSURE?
The article is devoted to the controversy regarding the identifi cation of the terms « petrotympanic fi ssure « and «Glyaser’s fi ssure». Fissura petrotympanica, well-known to the otolaryngologists, dentists and of cou...
CHANGES IN THE SURFACE OF DYING CELLS AND IM MUNE RESPONSE
Surface o f dying cells is undergoing changes, needed for their effective clearance by phagocytes. Ability o f dying cells to indicate to their microenvironment the necessity o f self-elimination is a key feature of apop...