Desmoplastic Ameloblastoma, a Difficult Pathological Entity to Diagnose Pre-Operatively-Review of Literature
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 3
Abstract
Philipsen and Reichart classified ameloblastomas (AM) into 4 subtypes, according to their clinical and biological behavior: intraosseous (solid/multicystic), extraosseous, unicystic, and desmoplastic. Histopathologically, conventional ameloblastoma subdivided into 6 subtypes, plexiform, follicular, granular cell, acanthomatous, basaloid and desmoplastic ameloblastoma. According to the literature desmoplastic ameloblastoma (DA) is a rare variant of ameloblastoma. It was first described by Eversole et al, in 1984 as an “ameloblastoma with pronounced desmoplasia” and later on it was further reviewed by Wardlon and El-Mofty et al, in 1987 and by Reichart et al, in 1995. In 2005 the World Health Organization declared DA as a distinct clinic-pathological entity. DA reportedly has a site predilection for the anterior regions of the jaw unlike other Ameloblastoma. Its unique radiographic appearance is that of a mixed radiolucent-radiopaque lesion unlike the strictly radiolucent quality of other ameloblastomas. In spite of the several scientific literatures, the true biologic profile of DA is still not well understood.
Authors and Affiliations
Dr. Ananya Das, Prof. (Dr. ) Sudip Chakraborty, Prof. (Dr. ) Amit Ray
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