DETERMINATION OF PARTIAL MOLAR PROPERTIES AND ACOUSTIC PARAMETERS OF AMINO ACIDS IN AQUEOUS METHANOL SOLUTIONS IN PRESENCE OF SODIUM BENZOATE
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2014, Vol 6, Issue 10
Abstract
Objective: To study the partial molar properties and acoustic parameters of amino acids in the solutions of 5, 10 and 15 wt %of aqueous methanol in presence of sodium benzoate.Methods: Effect on solute –solvent interaction is studied by determining the densities of pure solvents and the ultrasonic velocity of pure solvent and solutions is measured by using an ultrasonic interoferometer.Results: The results are discussed in the light of molecular interaction, ion-solvent interactions ion-solvent interactions dominate over ion-ion interactions, β-alanine has higher ion-solvent interaction than α-alanine & glycine.Conclusion: Overall,β-alanine shows high ion-solvent interaction due to higher mass which represents structural effect of solute on solvent in solution.Â
Authors and Affiliations
Smruti Pattnaik, Upendra Nath Dash
METHOD DEVELOPMENT AND VALIDATION FOR THE QUANTITATIVE ESTIMATION OF INDINAVIR IN CAPSULES BY RP-HPLC
Objective: To develop an accurate, precise and linear Reverse Phase High Performance Liquid Chromatographic (RP-HPLC) method and validate as per ICH guidelines for the quantitative estimation of Indinavir Sulphate (400mg...
CHARACTERIZATION OF POLYHYDROXYBUTYRATE SYNTHESIZED BY BACILLUS CEREUS
Objectives: To characterize the Polyhydroxybutyrate (PHB) produced from Bacillus cereus using various instrumental methods and reduce them to the nanoscale which can be used as drug carrierMethods: The isolated bacterium...
THE EFFECTS OF DIABETES MELLITUS ON THE RESPONSE TO PEGINTERFERON-ALPHA IN COMBINATION WITH RIBAVIRIN THERAPY IN EGYPTIAN CHRONIC HEPATITIS C PATIENTS
Objective: The present study aimed to determine whether type 2 diabetes mellitus influences the response to antiviral therapy with peg-interferon alpha plus ribavirin in Egyptian patients with chronic hepatitis C.Methods...
CYTOTOXICITY STUDY OF ANTIDIABETIC PLANTS ON NEUROBLASTOMA CELLS CULTURED AT NORMAL AND HIGH GLUCOSE LEVEL
Objective: In diabetes, chronic hyperglycemia causes damage (glucose toxicity) on some cells leading to micro and macro vascular complications. The aim of this study was to investigate the effect of antidiabetic plants e...
VIRTUAL SCREENING STUDIES OF SEAWEED METABOLITES FOR PREDICTING POTENTIAL PPARγ AGONISTS
Objective: Peroxisome Proliferator-Activated Receptor-gamma (PPARγ) is a crucial nuclear hormone receptor, which modulates the transcriptional regulation of lipid and glucose homeostasis. It plays a crucial role in many...