Diagnostic Utility of Hematological Scoring System in Detection of Neonatal Sepsis
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2018, Vol 7, Issue 11
Abstract
Background: Neonatal sepsis is one of the important causes of morbidity and mortality in the neonatal period. Objectives: To analyse the hematological findings according to Rodwells hematological scoring system and correlation with blood culture. Materials and methods: A Total of 120 neonates were included in the study. Blood samples from 120 neonates were subjected to blood culture and Hematological scoring system (HSS). They were divided in to 3 groups i.e group 1 (proven sepsis - 32), group 2 (probable sepsis - 56) and group 3 (Normal infant - 32). Results: Out of 120 infants, 32 had positive blood culture. Majority (66.6%) were preterm. Male to female ratio was 1.7:1. Out of 32 sepsis cases, 27 (84.3%) had predominant score was 5 >. Maximum number of cases 31 (55.31%)) showed score with 3-4 in probable sepsis group. Association of hematological parameters and scores was found to be statistically significant (p<0.05). Majority of parameters found to have high sensitivity while platelet count and Total Neutrophils count (TNC) had high specificity. Combination of hematological tests found to have high sensitivity and specificity when compared to single hematological test. Conclusion: Hematological scoring system is easy, cheap and cost effective screening tool for early diagnosis of neonatal sepsis.
Authors and Affiliations
Bheemaraju Venkata Vydehi
Keywords
Related Articles
- EP ID EP529981
- DOI 10.21088/ijprp.2278.148X.71118.1
- Views 70
- Downloads 0
Correlation of Cyclo-Oxygenase-2 (COX-2) Expression with Tumor Differentiation and Lymphovascular Invasion in Cervical Cancer
Background: Cyclo-Oxygenase-2 (COX-2) derived prostaglandins are known to participate in carcinogenesis, tumor cell invasion and metastasis. COX-2 is expressed in all stages of cancer and it’s over expression is associat...
Role of C Reactive Protein, White Blood Cell Counts, Polymorph Percentage and Histopathological Findings in Diagnosing Appendicitis
Background: Acute appendicitis is the most common surgical emergency associated with an acute phase reaction. The diagnosis of the same is based on detailed clinical history and examination, laboratory and imaging interv...
Cytomorphological Study of Cervical Lymph Node Lesions: A Study of 173 Cases
Introduction: Cervical lymph node enlargement is frequent presentation in all age groups with a wide spectrum of diseases, ranging from infections to malignancy. Therefore, management of cases depends on lymph node patho...
Intraoperative Squash Cytology of Central Nervous System Lesions: Review of an Eight-Year Experience
Background: Intraoperative squash cytology is a simple and reliable technique for rapid intraoperative diagnosis of neurosurgical specimens. Intraoperative squash cytology is a fairly accurate diagnostic modality which c...
Reproducibility of Modified Gleason Scoring System and Grade Group in Prostate Carcinoma on Microphotographs
Background: Pathologists can quickly transmit the microscopic images photographed in a certain location to remote centers for analyzing the images. Gleason scoring system forms an important prognostic parameter for thera...