DRY EMULSION: A PROMISING DOSAGE FORM TO DELIVER LIPOPHILIC DRUG MOLECULES WITH IMPROVED STABILITY AND EFFECTIVENESS
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 1
Abstract
Liquid emulsions have distinct advantages over the other oral dosage forms by improving the bio availability and by reducing the side effects, but the number of emulsion formulations currently in use are few compared with other oral dosage forms due to lack of physical - chemical and compliance problems. To overcome these problems dry emulsions are prepared. Dry emulsions are prepared by drying liquid o/w emulsions containing a solid carrier in the aqueous phase. The solid carrier provides the dry emulsions with bulk and mass. Dry emulsions are lipid based powder formulations from which an O/W emulsion can be reconstituted in-vivo or in-vitro. Dry emulsions can be prepared by spray drying, lyophilization and rotary evaporation. Unfortunately the dry emulsions were cohesive powders. The cohesiveness was reduced by addition of sucrose.
Authors and Affiliations
Haritha M, Priyanka M, Abeda Aqther, Neeharika R, Pragati Kumar
Keywords
Related Articles
- EP ID EP33012
- DOI -
- Views 434
- Downloads 0
Formulation and evaluation of herbal anti-dandruff shampoo
Dandruff is a common disorder affecting the scalp condition caused by yeast Pityrosporum. Dandruff cannot be completely eliminated but can only be managed and effectively controlled. A shampoo is a preparation containi...
STABILITY INDICATING RP-HPLC METHOD FOR THE SIMULTANEOUS DETERMINATION OF CANDESARTAN CILEXETIL AND HYDROCHLOROTHIAZIDE IN BULK AND DOSAGE FORMS
A simple, specific and accurate reverse phase high performance liquid chromatographic method was developed for the simultaneous determination of Candesartan cilexetil and Hydrochlorothiazide in pharmaceutical dosage fo...
Antioxidant property for lipophilic extract of Strobilanthes kunthiana flowers
Strobilanthes kunthiana flowers are found on the hill slopes of the Western Ghats at an altitude of 6000 to 7000 feet. It is a bright blue bell shaped flower. The uniqueness of the flower is that it blooms once in 12 y...
Effect of ethanol/water extract of Crinum jagus on glycemia, lipids parameters and body weight gain on high-sugar diet fed rats
Crinum jagus is used in Cameroon western region folk medicine in the management of diabetes and obesity. The effects of ethanol/water extract of C. jagus were evaluated on two month old Wistar rats submitted to a high...
Authentication of traditional crop Kalongi (Nigella sativa L.) by LAMP marker
Nigella sativa, commonly known as kalongi is an important drug of traditional system of medicine, commonly used against cough, fever, abdominal disorders, skin infections, paralysis and jaundice. Because of increased d...