Effect of aqueous extract of Amaranthus spinosus on hematological parameters of wistar albino rats
Journal Title: Journal of Experimental Biology and Agricultural Sciences - Year 2016, Vol 4, Issue 0
Abstract
Amaranthus spinosus is known for its various remedies against many ill conditions. Present study has been carried out to verify the toxic effects of whole plant’s aqueous extract against albino rats at hematological levels. The aqueous extract was administered orally at 125, 250, 500 and 1000 mg/Kg body wt./day respectively for 60 days; against distilled water administered control. Results of study did not show any mortality in all the treatment groups throughout the study period. The significant reduction in RBC, hemoglobin, PCV and MCHC and significant increase in WBC and MCV was observed at the dose level 1000 mg/Kg body wt/day. After 90 days of treatment withdrawal, the hematological parameters regained to control levels. The toxic effects found to be dose dependent as hematological parameters were altered only at higher dose level.
Authors and Affiliations
Bhande Satish S, Wasu Yogesh H
Keywords
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- EP ID EP426885
- DOI 10.18006/2016.4(1).116.120
- Views 77
- Downloads 0
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