Effect of circadian rhythms and gender in patients with ST-Segment elevated myocardial infarction
Journal Title: Medpulse International Journal of Physiology - Year 2017, Vol 3, Issue 3
Abstract
Background and Aim: The circadian rhythm, body’s biological clock, is known to influence a number of physiological and pathological processes in the body, including the development of acute myocardial infarction. Therefore, in our study, the role of circadian rhythm in patients with ST-Segment Elevated Myocardial Infarction (STEMI) has been studied. Methods: In this hospital-based, cross-sectional study, 200 patients were chosen as per the selection criteria from among the acute myocardial infraction (MI) patients admitted in the ICU, Department of Medicine, SRTR GMC, Maharashtra. Results: Of the 200 subjects, 164 (82%) survived MI while 36 (18%) developed complications. Maximum MI occurred early in the morning. A progressive increase was seen in the incidence of anterior wall myocardial infarction as age advances. There is a statistically significant higher occurrence of systemic hypertension in female subjects compared to the incidence of other comorbid illnesses among males and females. Conclusion: Occurrence of STEMI shows the first peak between 6 AM and 12 PM and the second peak between 12 PM to 6 PM. There is a statistically significant higher occurrence of systemic hypertension in female subjects compared to the incidence of other comorbid illnesses among males and females. There is no significant correlation between the time of onset of symptoms and complications in any particular gender. Mortality was higher in males and the deaths in each period were proportionate irrespective of the circadian pattern.
Authors and Affiliations
Sunita Handergulle, ,Sidheshwar V Birajdar, Ashishkumar Jain
Keywords
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