Effect of Primary Testicular Tumor Localization on Prognosis and Survival of Non-seminomatous Testis Cancer Patients
Journal Title: The Bulletin of Urooncology - Year 2020, Vol 19, Issue 3
Abstract
Objective: Unlike left testicular vein, right testicular vein drains into inferior vena cava. Consequently, the systemic spread of testicular cancers in each side is expected to differ based on the vascular structures of the right and left testis. In this study, we investigated the effect of tumour localization on survival of nonseminomatous testicular cancer patients. Materials and Methods: We included three hundred and twenty-one (321) non-seminomatous testicular cancer patients who were followed-up at Gülhane Training and Research Hospital between January 1981 and December 2015. Results: The primary tumour found in the left testis in 152 (47.2%) patients, while 170 (52.8%) patients had the primary tumour in the right testis. The lungs (n=62, 42.5%) was the most common site of metastasis. During follow-up and primary treatment, 74 (23.1%) patients had recurrence, which was common in retroperitoneal lymph nodes (10.3%) and lung (5%). Median follow-up period was 88.3 (range: 1-386) months, while median survival was 337 months in all cases. Median 10 year survival rate was 74.1%, while median 20 year survival rate was 70.7%. We found that survival of patients with the primary tumour was significantly different between the left and right testis (337.6 months vs denotes not reached, p=0.001). The recurrence rate was significantly higher (84.7% vs 68.2%; p=0.002) in patients with right testicular tumour when compared to patients with left testicular tumour. Conclusion: The survival of the patients with tumour localized in the right testis was higher than patients with tumour localized in the left testis.
Authors and Affiliations
Birol Yıldız, Ece Esin, Bilgin Bahadır Başgöz, İsmail Ertürk, Ramazan Acar, Nuri Karadurmuş
Keywords
Related Articles
- EP ID EP688792
- DOI 10.4274/uob.galenos.2020.1672
- Views 124
- Downloads 0
Risk of Neoplastic Squall Downstream Cytokine Storm of COVID-19 in Male Patients
No summary
The Current Strategies for Neoadjuvant Chemotherapy in Muscle Invasive Bladder Cancer: The Place of Immunotherapy in Future
Muscle invasion is present in approximately thirty percent of bladder cancers. Radical cystectomy and bilateral pelvic lymph node dissection following neoadjuvant chemotherapy is the recommended treatment for muscle inva...
Multiparametric MRI Fusion-guided Biopsy for the Diagnosis of Prostate Cancer: Results of the First 100 Consecutive Patients
Objective: Our aim was to compare prostate cancer detection rates according to International Society of Urological Pathology (ISUP) grade group (GG) among magnetic resonance imaging (MRI)-targeted biopsies (TBx), systema...
Intravesical Mitomycin-C with Bladder Wall Hyperthermia in Intermediate and High-risk Non-muscle Invasive Bladder Cancers: Prospective Clinical Trial with a Singletreatment Arm
Objective: Bacillus Calmette-Guérin (BCG) limited availability, cost, and allergic response in some patients limit its use, leading to the search for alternative agents. We aimed to present the outcomes of intermediate-...
The Role of Adrenal Cortex-Sparing Surgery for Bilateral Masses in Three Cases
Pheochromocytoma are the functional adrenal lesions originating from the chromaffin cells. For the cases of pheochromocytoma observed in multiple endocrine neoplasia Type 2 and Von Hippel syndrome, the bilateral adrenal...