The Role of Adrenal Cortex-Sparing Surgery for Bilateral Masses in Three Cases
Journal Title: The Bulletin of Urooncology - Year 2020, Vol 19, Issue 1
Abstract
Pheochromocytoma are the functional adrenal lesions originating from the chromaffin cells. For the cases of pheochromocytoma observed in multiple endocrine neoplasia Type 2 and Von Hippel syndrome, the bilateral adrenal glands are involved. In classical approach, total adrenalectomy is applicable on such masses while adrenal failure is almost inevitable. Lifelong cortisol and fludrocortisones replacement are necessary for the patients with adrenal failure while the rate of morbidity and mortality has significantly increased. With the introduction of the minimal invasive surgical approach, cortex sparing adrenalectomy has been brought forward for the adrenal tumors. The primary objective of the cortex sparing surgery is to prevent the lifelong replacement and the permanent adrenal failure after adrenalectomy. Therefore, it is particularly preferred in the case of genetic pheochromocytoma with bilateral adrenal involvement. However, in the case of the selected cases, it can also be applicable for adenoma producing aldostrerone and Cushing syndrome. The adrenal tumor will be completely removed and if sufficient tissue is reserved in the manner to preserve the cortex function, no long-term recurrence and adrenal failure is to be developed. Therefore, cortex-sparing surgery may be a good alternative to total adrenalectomy for the patients with small benign functional adrenal tumors or bilateral genetic pheochromocytoma.
Authors and Affiliations
Elif Kılıç Kan, Ender Özden, Ayşegül Atmaca, Ramis Çolak
Keywords
Related Articles
- EP ID EP685425
- DOI 10.4274/uob.galenos.2019.1237
- Views 152
- Downloads 0
Renal Cell Carcinoma: Epidemiological Profile and Histopathological Features
Objective: Nowadays, with the use of advanced imaging methods, the incidence of renal cell carcinomas (RCCs) has increased steadily and they have become recognizable at early stage. Morphologically and immunophenotypical...
Key Steps in Robotic Simple Prostatectomy for Benign Prostatic Hyperplasia
Open prostatectomy is still an option for the surgical treatment of benign prostate hyperplasia (BPH). In this video, key steps in robotic simple prostatectomy are summarised. Robotic surgery provides a reasonable altern...
Management of Patients with Urological Cancers in Turkey during the COVID-19 Pandemic: Recommendations of Uro-oncology Association
Coronavirus disease-19 (COVID-19) has been declared as a pandemic by the World Health Organization. The number of cases has increased over time in correlation with the increasing number of testing worldwide. In order to...
The Effect of Tumor Localization and Clinicopathological Factors on Intravesical Recurrence and Survival in Primary Upper Urinary Tract Urothelial Tumors
Objective: We aimed to investigate the factors affecting intravesical recurrence and survival in patients undergoing radical nephroureterectomy and bladder cuff excision due to primary upper urinary system urothelial tum...
The Factors Affecting Recurrence and Prognosis in Patients with Low-grade Stage Ta Bladder Cancer
Objective: This study aims to review the parameters affecting tumour recurrence, tumour progression and cancer survival of patients with low-grade non-muscle invasive bladder cancer. Materials and Methods: We retrospect...