Effect of sodium selenite on thyroid gland functioning and efficacy of chemotherapy in tuberculosis patients with a concomitant diabetes mellitus and autoimmune thyroiditis

Journal Title: Актуальна інфектологія - Year 2017, Vol 5, Issue 5

Abstract

In 40 tuberculosis patients with diabetes mellitus and autoimmune thyroiditis ultrasonic research of thyroid structure and measurement of levels of free thyroxine, thyroid stimulating hormone, antibodies to thyroglobulin and peroxidase and selenium in the serum of blood were conducted by immune-enzyme method at the beginning and at the end of the phase of intensive chemotherapy depending on the prescribing of sodium selenite. Efficacy of antituberculosis chemotherapy was estimated by general clinical, bacteriological and X-ray criteria. Autoimmune thyroiditis with the phenomena of subclinical hypothyroidism is diagnosed for all investigational persons. Prescribing of sodium selenite during the phase of intensive chemotherapy promotes the recovery of thyroid function. Rates of intoxication symptoms elimination, abacillation reduction and healing of the cavities at the end of intensive phase of chemotherapy were for certain higher in the group of patients with prescribing of sodium selenite.

Authors and Affiliations

S. L. Matveyeva, N. N. Tyazhlova, K. V. Yakovleva, S. O. Matveyev

Keywords

Related Articles

Aldosterone synthase gene polymorphism in alimentary obesity, metabolic syndrome components, some secondary forms of arterial hypertension, pathology of the adrenals glands core (literature review)

Hormonal factors of adrenal origin belong to the pathophysiological mechanisms of the formation and progression of arterial hypertension (AH) and should be consi­dered while developing differentiated approaches to the tr...

On the Early Detection of Streptococcal Tonsillopharyngitis in Children

Urgency of the problem of diagnosis and treatment for acute tonsillopharyngitis is due to their considerable prevalence among children population (12 to 17 %). Inadequate treated acute tonsillopharyngitis, especially cau...

Сlinical and Sonographic Indices as Diagnostic Criteria of Infectious Mononucleosis in Children

Introduction. Significant polymorphism of clinical manifestations of infectious mononucleosis, multisystemic lesions, frequent lack of clear clinical and paraclinical criteria and delayed results of available laboratory...

Contraceptive Vaccines

Researches to develop vaccines with contraceptive effect are being carried out since the 1920s. Since 1972, the contraceptive vaccines are one of the priority programs of the World Health Organization (WHO Special Progra...

Reiter’s Disease as a Manifestation of Intestinal Infections

There are considered the role of enteropathogenic bacterial factors, in particular yersiniosis infection, in the development of Reiter’s disease, incidence rate in the clinical practice of an infectiologist, and features...

Download PDF file
  • EP ID EP264069
  • DOI 10.22141/2312-413x.5.5.2017.121639
  • Views 105
  • Downloads 0

How To Cite

S. L. Matveyeva, N. N. Tyazhlova, K. V. Yakovleva, S. O. Matveyev (2017). Effect of sodium selenite on thyroid gland functioning and efficacy of chemotherapy in tuberculosis patients with a concomitant diabetes mellitus and autoimmune thyroiditis. Актуальна інфектологія, 5(5), 246-249. https://europub.co.uk./articles/-A-264069