Effects of Fungicide Propiconazole on Oxidative Stress Parameters and Antioxidant System Enzymes in Liver of Oreochromis niloticus
Journal Title: JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES - Year 2019, Vol 4, Issue 1
Abstract
In this research, 0.5 ppb and 2.5 ppb effect of fungicide propiconazole in 7 days and 28 days periods in liver tissue of Oreochromis niloticus, superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and glutathione S transferase (GST) antioxidant system enzyme activities and oxidative stress parameters glutathione (GSH) and thiobarbituric acid reagents (TBARS) were determined by spectrophotometric methods. In our study, GSH levels and GSH-dependent GPx and GST activity increased in 7 days. In 28 days, decrease in GSH and increase in GST activities were determined. SOD and CAT activities increased in 7 days and decreased in 28 days. In TBARS levels, the time and concentrations -related increase in the effect of propiconazole According to the results of the study; The effect of propiconazole on antioxidant enzyme activity and oxidative stress parameters in O. niloticus was determined to cause hepatotoxic effect.
Authors and Affiliations
Özge Temiz
Keywords
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- EP ID EP558297
- DOI 10.35229/jaes.532079
- Views 79
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