Efficacies of Eruca sativa and Raphanus sativus Seeds’ Oils in Streptozotocin-Induced Diabetic Rats
Journal Title: International Journal of Clinical Endocrinology and Metabolism - Year 2016, Vol 2, Issue 1
Abstract
Objective: The study was planned to investigate the effect of Eruca sativa seeds’ oil (ESSO) and Raphanus sativus seeds’ oil (RSSO) on impaired glucose tolerance, lipid profile and oxidative stress in streptozotocin-induced diabetic albino rats. Also, the probable mechanisms of action were suggested. Methods: Experimental diabetes mellitus was induced by a single dose of 45 mg/kg b. wt streptozotocin. The diabetic rats were then divided into three groups: the 1st one was given 1% caboxymethylecellulose (CMC) and was considered as diabetic control, the 2nd group was treated with 50 mg/kg b. wt ESSO dissolved in 5 ml CMC and the 3rd group was treated with 50 mg/kg b. wt. RSSO dissolved in 5 ml CMC by gastric intubation daily for 30 days. The diabetic control rats were compared with normal group.
Authors and Affiliations
Ahmed Osama M, Abdel-Reheim Eman S, Ashour Mohammed B, Fahim Hanaa I, Mohamed Hassnaa H
Keywords
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- EP ID EP542367
- DOI 10.17352/ijcem.000021
- Views 50
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