Efficacy of Cefazolin and Cefotaxime in the treatment of mandibular fractures and teeth involved- A comparative study.
Journal Title: International Journal of Medical Science And Advanced Clinical Research (IJMACR) - Year 2018, Vol 1, Issue 5
Abstract
Aim: The purpose of this study is to establish a relationship between mandibular fracture sites, vitality of teeth in the line of fracture, displacement of the fractured segments treated with open reduction and fixation and to evaluate the function and outcome of teeth retained after administration of Cefazolin and Cefotaxime. Materials and Methods: Data was collected from 56 patients treated by open reduction and internal fixation for 71 mandibular fractures during a mean follow up of 14 months with a mean age of 34 years at oxford dental college. Outcome variables were pulp vitality of the teeth involved and post operative infection after intravenous administration of Cefazolin and Cefotaxime respectively. The relationship of demographic variables, teeth involved in the line of fracture and the management of fractured segments were analyzed using Mann Whitney and Chi Square test. Results: The mean age of Group A was 30.6 years (SD of 11) and that of Group B was 31.3 years (SD of 10.2) and the p- value was 0.77a with a male to female ratio of 78.6%: 21.4% in Group A and 82.1%: 17.9% in Group B with a p- value of 0.74b. Out of 28 fracture sites in Group A; 20 teeth (71.4%) were retained in which 2 teeth (66.7%) showed post operative complications and required root canal treatment whereas, 1tooth (33.3%) got re- infected and was later extracted. On the other hand, out of 28 fracture sites in Group B; 23 teeth (82.1%) were retained in which 2 teeth (66.7%) teeth were re- infected and had to be extracted while 1 tooth (33.3%) required root canal treatment. Parasymphysis fracture was the most common type with an incidence of 39.3% in Group A and 21.4% in Group B respectively; while bilateral parasymphysis and body fracture were the least common with an incidence of 0% in Group A and 3.6% in Group B. Conclusion: There is an increased risk for post operative complications when teeth in the line of fracture are extracted; though it is statistically insignificant. Evaluation of fate of retained teeth showed better prognosis of Type I and II as compared to Type III and Type IV. Results conclude that teeth involved in mandibular fractures need not be removed as a prophylactic measure and the administration of Cefazolin showed better post operative results as compared to Cefotaxime.
Authors and Affiliations
Dr. Harish Kumar. A.
Keywords
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