Escherichia coli 0517:H7: An emerging bacterial zoonotic food borne pathogen of global significance
Journal Title: International Journal of Interdisciplinary and Multidisciplinary Studies (IJIMS) - Year 2016, Vol 4, Issue 1
Abstract
In recent years, Escherichia coli 0157: H7, a Gram negative bacterium, has emerged as an important global zoonotic food borne pathogen, which produces serious illness in humans such as haemorragic colitis, haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). The patient who develops TTP carries a fatality rate of 50 %, and death in HUS is due to renal failure. Cattle are considered as the primary reservoir of this pathogen. Faecal-oral- route is the chief mode of transmission. Humans may acquire infection by the ingestion of raw ground beef, other animal products and contaminated fruits and vegetables, direct contact with animal carriers, their faeces and contaminated soil or water. The raw or undercooked ground beef is implicated in several outbreaks of disease. The infection can result in life threatening complications in young children, elderly persons, and immunocompromised patients. Microbiological and molecular techniques are employed for the isolation and characterization of Escherichia coli o157:H7. Sanitary operations in abattoirs, good personal hygiene, proper disposal of faeces,use of chlorinated water, ingestion of pasteurized milk, thorough washing of fruits and vegetables, and public education about the consumption of cooked meat will certainly help to reduce the incidence of this emerging pathogen which pose a global threat to public health. It is emphasized to undertake further studies on the faecal carriage of other food animals, risk factors, host agent interaction, and simple and cheap diagnostic test for this emerging food borne zoonotic pathogen.
Authors and Affiliations
Mahendra Pal, Raj Mahendra
Keywords
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