Evaluation of effect of tobacco smoking on Absolute eosinophil count and Peak expiratory flow rate in male volunteers
Journal Title: Perspectives In Medical Research - Year 2016, Vol 4, Issue 2
Abstract
Introduction: Tobacco smoking in India has been increasing alarmingly. Smoking is a known risk factor for chronic obstructive pulmonary disease, cardiovascular diseases and certain cancers, especially, the lung cancer. Objectives: To assess the effects of tobacco smoking on Peak expiratory flow rate (PEFR) and absolute eosinophil count (AEC) in male volunteers. Material and Methods: : The study population divided into two groups study (n=40, male smokers ) and control group (n=40, non smokers).Subjects were aged between 18 to 26 years. PEFR was measured by using Wright’s mini Peak Flow Meter and AEC was done by using Neubauer counting chamber Results: PEFR was lower in smokers when compared to non-smokers which was statistically significant (p < 0.05). However, mean eosinophil count was higher in smokers when compared to non-smoker (p < 0.05). The correlation between PEFR and AEC was not statistically significant. Conclusion: The mean AEC showed higher value in smokers. But PEFR were significantly lower in male smokers compared to non-smokers. A significant decrease in the PEFR and an increase in the AEC with severity of cigarette smoking were observed. The relationship between PEFR and AEC was not statistically significant.
Authors and Affiliations
Srinivasa Jayachandra
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