EVALUATION OF EFFICACY OF EPIDURAL BUTORPHANOL TARTRATE FOR POSTOPERATIVE ANALGESIA
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 2
Abstract
Objectives: The objective of this study was to evaluate the efficacy of epidural butophanol tartrate in postoperative analgesia and to monitor its side effects.Methods: 80 patients of ASA 1 and 2 scheduled for elective abdominal and gynaecological procedure were chosen for the study. At the end of surgery, study group received 2mg of butorphanol in 10 ml normal saline through an epidural catheter and the control group received 10 ml of normal saline. Postoperatively vitals, VAPS, sedation score and side effects were pointed. Patients received rescue analgesic when VAPS was greater than 6.Results: Epidural butorphanol produced duration of analgesia of 7.46 ± 1.35 hours. The quality of analgesia was excellent in 75% of patients and good in 25% of patients. The two main adverse effects observed were sedation and vomiting. Sedation may be beneficial to patients in the immediate postoperative period.Conclusion: Epidural butorphanol produces long lasting, good quality analgesia with minimal side effects.Â
Authors and Affiliations
R. Venkatraman
Keywords
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